Clinical trial Recruiting at 1 site Interventional Ages 40 to 74

One-time low-dose CT scan for lung cancer screening

Official title: Non-risk Based Lung Cancer Screening With One-time Low-dose Computed Tomography: a Prospective Cohort Study

Run by The First Affiliated Hospital of Guangzhou Medical University · NCT04938804 · Data updated 2026-11-12

This study is testing if a one-time low-dose CT scan can help find lung cancer early in people aged 40-74 living in Guangzhou, regardless of their risk factors.

More Lung Cancer trials

Quick facts

Study typeInterventional
Ages40 Years to 74 Years
SexAll
Enrollment11000 (estimated)
SponsorThe First Affiliated Hospital of Guangzhou Medical University
Academic / other
Locations1 site (Guangzhou, Guangdong)
StatusRecruiting
StartedDecember 12, 2015
Main results expectedDecember 1, 2025
Study endsDecember 1, 2026
Registry record updatedJanuary 9, 2024
Trial IDNCT04938804 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are residents aged 40-74 years living in Guangzhou without a recent history of lung cancer or significant cancer-related symptoms.

Probably not a fit

Patients who have been diagnosed or treated for lung cancer in the past five years or have significant cancer-related symptoms may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

The Guangzhou Lung-Care Project is a single-arm, prospective cohort initiative aimed at early lung cancer detection using a one-time low-dose computed tomography (LDCT) scan. It recruits residents aged 40-74 from four communities in Guangzhou, focusing on the lung cancer detection rate among participants without high-risk factor restrictions. The study also examines the proportion of stage I lung cancer cases and investigates various factors associated with lung cancer development. Follow-up for post-screening management and survival outcomes is recorded to assess the effectiveness of the screening approach.

Why it matters

Potential benefit: If successful, this study could lead to earlier detection of lung cancer, potentially improving survival rates for patients.

How similar studies have gone: Other studies have shown success with similar low-dose CT screening approaches for lung cancer detection, indicating potential effectiveness.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Minimum age of 40 years among the residents in Guangzhou

Exclusion Criteria:

* Persons who had a diagnosis or treatment related to LC within the past 5 years, had undergone chest CT within the past year, or had significant cancer-related symptoms (e.g., hemoptysis, dyspnea, inability to climb two flights of stairs).

Where it's running

  • The First Affiliated Hospital of Guangzhou Medical University
    Guangzhou, Guangdong, China
    Recruiting

Study contacts

  • Principal investigator: Wenhua Liang, MD — The First Affiliated Hospital of Guangzhou Medical University
  • Study coordinator: Wenhua Liang, MD
  • Email: liangwh1987@163.com
  • Phone: +86-02-83062808

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.