One-time low-dose CT scan for lung cancer screening
Non-risk Based Lung Cancer Screening With One-time Low-dose Computed Tomography: a Prospective Cohort Study
NA · The First Affiliated Hospital of Guangzhou Medical University · NCT04938804
This study is testing if a one-time low-dose CT scan can help find lung cancer early in people aged 40-74 living in Guangzhou, regardless of their risk factors.
Quick facts
| Phase | NA |
|---|---|
| Study type | Interventional |
| Enrollment | 11000 (estimated) |
| Ages | 40 Years to 74 Years |
| Sex | All |
| Sponsor | The First Affiliated Hospital of Guangzhou Medical University (other) |
| Locations | 1 site (Guangzhou, Guangdong) |
| Trial ID | NCT04938804 on ClinicalTrials.gov |
What this trial studies
The Guangzhou Lung-Care Project is a single-arm, prospective cohort initiative aimed at early lung cancer detection using a one-time low-dose computed tomography (LDCT) scan. It recruits residents aged 40-74 from four communities in Guangzhou, focusing on the lung cancer detection rate among participants without high-risk factor restrictions. The study also examines the proportion of stage I lung cancer cases and investigates various factors associated with lung cancer development. Follow-up for post-screening management and survival outcomes is recorded to assess the effectiveness of the screening approach.
Who should consider this trial
Good fit: Ideal candidates for this study are residents aged 40-74 years living in Guangzhou without a recent history of lung cancer or significant cancer-related symptoms.
Not a fit: Patients who have been diagnosed or treated for lung cancer in the past five years or have significant cancer-related symptoms may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to earlier detection of lung cancer, potentially improving survival rates for patients.
How similar studies have performed: Other studies have shown success with similar low-dose CT screening approaches for lung cancer detection, indicating potential effectiveness.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Minimum age of 40 years among the residents in Guangzhou Exclusion Criteria: * Persons who had a diagnosis or treatment related to LC within the past 5 years, had undergone chest CT within the past year, or had significant cancer-related symptoms (e.g., hemoptysis, dyspnea, inability to climb two flights of stairs).
Where this trial is running
Guangzhou, Guangdong
- The First Affiliated Hospital of Guangzhou Medical University — Guangzhou, Guangdong, China (RECRUITING)
Study contacts
- Principal investigator: Wenhua Liang, MD — The First Affiliated Hospital of Guangzhou Medical University
- Study coordinator: Wenhua Liang, MD
- Email: liangwh1987@163.com
- Phone: +86-02-83062808
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Lung Cancer, Screening