Oncology care coordination program for Native American patients

Care Coordination and Communication Program in Oncology for Tribal Health Systems (C3PO)

University of Oklahoma · NCT07217574

This project will test whether a coordinated care and navigation program (C3PO) helps Native American adults newly diagnosed with cancer communicate with care teams and report better outcomes.

Quick facts

Study typeObservational
Enrollment187 (estimated)
Ages18 Years and up
SexAll
SponsorUniversity of Oklahoma (other)
Locations1 site (Oklahoma City, Oklahoma)
Trial IDNCT07217574 on ClinicalTrials.gov

What this trial studies

The program uses a two-phase approach enrolling Native American adults with newly diagnosed cancer who are navigated through the NANP at OU Health Stephenson Cancer Center. Phase I is a 3-month pilot with up to 15 participants completing baseline assessments, monthly surveys, and exit interviews to refine the intervention. Phase II is a randomized trial comparing the C3PO care coordination intervention to usual navigation services, with all participants offered C3PO after six months. C3PO meetings focus on treatment side effects, comorbidities, approvals for referred care, and practical barriers such as transportation and financial hardship.

Who should consider this trial

Good fit: Native American adults (18+) within eight weeks of a new cancer diagnosis who are navigated through the NANP at OU Health Stephenson Cancer Center and speak English fluently.

Not a fit: People who are not Native American, diagnosed more than eight weeks earlier, not enrolled in the NANP navigation program, non-English speakers, or who participated in the Phase I pilot (and are therefore ineligible for Phase II) may not receive benefit from this trial.

Why it matters

Potential benefit: If successful, this program could reduce care barriers, improve symptom management, and lead to better patient-reported outcomes for Native American cancer patients.

How similar studies have performed: Care navigation and coordination programs have improved outcomes in other populations, but a culturally tailored program embedded with tribal health systems like C3PO is relatively novel and not extensively tested.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Participants must be at least 18 years of age, within eight weeks of newly diagnosed cancer confirmed by pathology/imaging, navigated through the NANP at SCC and have verbal fluency in English.

Exclusion Criteria:

* Participants in the Phase 1 open pilot will not be eligible for the Phase 2 RCT.

Where this trial is running

Oklahoma City, Oklahoma

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Patient Outcomes, American Indian, American Native

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.