Omitting drains after surgery for peptic ulcer perforations
Omitting of Usage of Intraabdominal Drains After Repair of Peptic Ulcer Perforations Compared to Traditional Use of Drains; Comparative Study
This study is testing whether patients who have emergency surgery for a perforated duodenal ulcer can recover just as well without using drains compared to those who do have drains.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 120 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Cairo University Academic / other |
| Locations | 1 site (Cairo) |
| Trial ID | NCT06084741 on ClinicalTrials.gov |
What this trial studies
This study evaluates the outcomes of omitting intraabdominal drains in patients undergoing emergency surgery for perforated duodenal ulcers. Patients will be randomly assigned to either receive drains or not after their surgical repair. The primary outcomes measured will include the length of hospital stay and pain scores. Data will be analyzed using SPSS version 21, with qualitative data presented as numbers and percentages, and quantitative data as means and standard deviations.
Who should consider this trial
Good fit: Ideal candidates are adults over 18 years old with perforated peptic ulcers who are undergoing exploratory laparotomy or laparoscopy.
Not a fit: Patients with preoperative shock, delayed presentation, or known malignant gastric ulcers will not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could reduce hospital stays and improve pain management for patients undergoing surgery for peptic ulcer perforations.
How similar studies have performed: Other studies have shown promising results with similar approaches, suggesting that omitting drains may be beneficial in specific surgical contexts.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: - Patients older than 18 years with perforated peptic ulcer who underwent exploratory laparotomy or laparoscopy and repair with omental pedicle techniques will included in the study. Exclusion Criteria: * preoperative shock on admission. * Delayed presentation more than 24 hours. * known malignant gastric ulcers confirmed by histopathology. * the presence of neuropsychiatric disease, pregnant and lactating women. * predisposing factors for impaired wound healing (e.g., currently using immunosuppressive agents, or chronic use of steroids), the presence of HIV/AIDS. * Intraoperative findings consistent with malignant ulcers. • American Society of Anesthesiologists grade III/IV, or had an alternative perioperative diagnosis. • Ulcer size more than 2 cm in diameter.
Where this trial is running
Cairo
- Cairo University — Cairo, Egypt (Recruiting)
Study contacts
- Principal investigator: Mohammed ElShwadfy — Cairo University
- Study coordinator: Mohammed ElShwadfy
- Email: m.elshwadfy1988@gmail.com
- Phone: +201025524630
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.