Obstructive sleep apnea in children and a narrow upper jaw.
Official title: Obstructive Sleep Apnea Hypopnea Syndrome (OSAHS) and Transverse Orthodontic Deficiency in Children
Run by Fondation Hôpital Saint-Joseph · NCT07086612 · Data updated 2026-11-12
This project will test whether children aged 6–16 who have a narrow upper jaw are more likely to have obstructive sleep apnea, using overnight sleep studies.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 6 Years to 16 Years |
| Sex | All |
| Enrollment | 102 (estimated) |
| Sponsor | Fondation Hôpital Saint-Joseph Academic / other |
| Locations | 1 site (Rouen) |
| Status | Recruiting |
| Started | November 6, 2025 |
| Main results expected | September 1, 2026 |
| Study ends | September 30, 2026 |
| Registry record updated | March 30, 2026 |
| Trial ID | NCT07086612 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Children aged 6 to 16 with a documented transverse maxillary deficiency or other orthodontic malocclusions whose parents or legal guardians provide consent and who can attend the Rouen clinic are ideal candidates.
✕Probably not a fit
Children without transverse maxillary issues, those outside the 6–16 age range, or those unable or unwilling to undergo overnight polysomnography are unlikely to receive benefit from this protocol.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This interventional study compares children with a transverse maxillary deficiency to children with other orthodontic issues to explore a possible causal link with obstructive sleep apnea. Eligible participants aged 6–16 will undergo an overnight ventilatory polysomnograph test to document sleep-disordered breathing. Groups are defined by orthodontic presentation (transverse deficiency versus other malocclusions) and clinical/polysomnographic criteria will be used for diagnosis. The work is conducted at the oral and cranio-maxillofacial orthopedics service in Rouen and requires parental consent for participation.
Why it matters
Potential benefit: If successful, this could enable earlier identification of children whose upper jaw problems contribute to sleep apnea and support targeted orthodontic treatments that improve breathing and sleep.
How similar studies have gone: Previous research has shown that rapid maxillary expansion can reduce symptoms of pediatric obstructive sleep apnea, but a direct causal link between transverse orthodontic deficiency and OSA remains not fully proven.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patient aged between 6 and 16 years * Patients with a transverse orthodontic deficiency (group "CAS") * Patients with another type of orthodontic deficiency (group "CONTROL") such as tooth rotation, crowding, mild Angle Class II or Class III dental occlusion * Patient who has given free, informed oral consent * Patient whose legal representatives have given their free written consent * Patient affiliated with a health insurance scheme Exclusion Criteria: * Patients refusing to participate in the study * Patients whose legal representatives refuse to participate in the study
Where it's running
-
Service d'orthopédie dento-cranio-maxillo faciale
Rouen, France Recruiting
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.