Clinical trial Recruiting at 1 site Interventional Ages 6 to 16

Obstructive sleep apnea in children and a narrow upper jaw.

Official title: Obstructive Sleep Apnea Hypopnea Syndrome (OSAHS) and Transverse Orthodontic Deficiency in Children

Run by Fondation Hôpital Saint-Joseph · NCT07086612 · Data updated 2026-11-12

This project will test whether children aged 6–16 who have a narrow upper jaw are more likely to have obstructive sleep apnea, using overnight sleep studies.

Quick facts

Study typeInterventional
Ages6 Years to 16 Years
SexAll
Enrollment102 (estimated)
SponsorFondation Hôpital Saint-Joseph
Academic / other
Locations1 site (Rouen)
StatusRecruiting
StartedNovember 6, 2025
Main results expectedSeptember 1, 2026
Study endsSeptember 30, 2026
Registry record updatedMarch 30, 2026
Trial IDNCT07086612 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Children aged 6 to 16 with a documented transverse maxillary deficiency or other orthodontic malocclusions whose parents or legal guardians provide consent and who can attend the Rouen clinic are ideal candidates.

Probably not a fit

Children without transverse maxillary issues, those outside the 6–16 age range, or those unable or unwilling to undergo overnight polysomnography are unlikely to receive benefit from this protocol.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This interventional study compares children with a transverse maxillary deficiency to children with other orthodontic issues to explore a possible causal link with obstructive sleep apnea. Eligible participants aged 6–16 will undergo an overnight ventilatory polysomnograph test to document sleep-disordered breathing. Groups are defined by orthodontic presentation (transverse deficiency versus other malocclusions) and clinical/polysomnographic criteria will be used for diagnosis. The work is conducted at the oral and cranio-maxillofacial orthopedics service in Rouen and requires parental consent for participation.

Why it matters

Potential benefit: If successful, this could enable earlier identification of children whose upper jaw problems contribute to sleep apnea and support targeted orthodontic treatments that improve breathing and sleep.

How similar studies have gone: Previous research has shown that rapid maxillary expansion can reduce symptoms of pediatric obstructive sleep apnea, but a direct causal link between transverse orthodontic deficiency and OSA remains not fully proven.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Patient aged between 6 and 16 years
* Patients with a transverse orthodontic deficiency (group "CAS")
* Patients with another type of orthodontic deficiency (group "CONTROL") such as tooth rotation, crowding, mild Angle Class II or Class III dental occlusion
* Patient who has given free, informed oral consent
* Patient whose legal representatives have given their free written consent
* Patient affiliated with a health insurance scheme

Exclusion Criteria:

* Patients refusing to participate in the study
* Patients whose legal representatives refuse to participate in the study

Where it's running

  • Service d'orthopédie dento-cranio-maxillo faciale
    Rouen, France
    Recruiting

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.