Observing walking patterns in patients with neuromuscular diseases

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to assess variations in gait parameters among patients with neuromuscular diseases, including muscular dystrophies, myopathies, spinal muscular atrophy, and Charcot-Marie-Tooth disease. The study will involve a clinical test to objectively measure fatigue during walking and will also evaluate the feasibility of using wearable sensors to monitor physical activity in daily life over a one-week period. By collecting this data, the researchers hope to gain insights into the impact of these conditions on mobility and daily functioning.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Ambulant adult patients with genetic diagnosis of muscular dystrophy/myopathy (dystrophinopathies, muscular dystrophies and congenital and non-congenital myopathies), of spinal muscular atrophy (SMA) and with molecular diagnosis of Charcot-Marie Tooth 1 or 2.
* independent walking, even with assistance;

Exclusion Criteria:

* Dilated or ischemic heart disease with moderate impairment;
* Chronic respiratory failure: forced vital capacity (FVC) \< 40%; more than 5% of nocturnal time spent with peripheral oxygen saturation levels \< 90.

Where it's running

• Scientific Institute IRCCS E. Medea - Sede di Bosisio Parini
  Bosisio Parini, Lecco, Italy Recruiting
• Scientific Institute IRCCS E. Medea - Polo di Conegliano
  Conegliano, Treviso, Italy Not yet recruiting

Study contacts

• Study coordinator: Fabio A Storm, PhD
• Email: fabio.storm@lanostrafamiglia.it
• Phone: +39031877111

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.