Observing treatments for severe coronary artery disease

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to track the long-term clinical outcomes of patients with unprotected left main coronary artery disease. It evaluates the effectiveness of three treatment approaches: medical therapy, coronary stenting with drug-eluting stents, and coronary artery bypass grafting (CABG). The study will collect data from approximately 5000 patients across 65 centers in the Asia-Pacific region, providing insights into real-world treatment results. The findings will help inform best practices for managing this serious condition.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Significant unprotected left main stenosis (\>50% by visual estimation)

  * The LMCA is considered unprotected if there are no patent coronary artery bypass grafts to the left anterior descending artery or the left circumflex artery.
* No limitation of clinical or lesion characteristics
* Age \>18 years
* The patient or guardian agrees to the study protocol and the schedule of clinical follow-up, and provides informed, written consent, as approved by the appropriate Institutional Review Board/Ethics Committee of the respective clinical site.

Exclusion Criteria:

* Protected left main stenosis

Where it's running

• Zhongshan Hospital
  Shanghai, China Recruiting
• Sarawak General Hospital
  Kuching, Malaysia Recruiting
• Hallym University medical center
  Anyang, South Korea Recruiting
• Inje University Busan Paik Hospital
  Busan, South Korea Recruiting
• Soonchunhyang University Hospital, Cheonan
  Cheonan, South Korea Recruiting
• Daegu Catholic University Medical Center
  Daegu, South Korea Recruiting

Study contacts

• Principal investigator: Seung-Jung Park, MD, PhD — Cvrf
• Study coordinator: Seung-Jung Park, MD, PhD
• Email: sjpark@amc.seoul.kr
• Phone: 82-2-3010-3152

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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• Intraoperative Pulse Pressure Variation and Postoperative Lactate Clearance in CABG Patients

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.