Observing the effects of rimegepant on migraine treatment in the Greater Bay Area

A Registry Study on Rimegepant for the Treatment of Migraine Participants in Guangdong-Hong Kong-Macao Greater Bay Area

Observational Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University · NCT06221267

This study is trying to see how well rimegepant works for treating migraines and improving the daily lives of people in the Greater Bay Area.

Quick facts

Study typeObservational
Enrollment120 (estimated)
Ages18 Years and up
SexAll
SponsorSun Yat-Sen Memorial Hospital of Sun Yat-Sen University Academic / other
Locations1 site (Guangzhou, Guangdong)
Trial IDNCT06221267 on ClinicalTrials.gov

What this trial studies

This observational registry study aims to enroll 120 migraine patients treated with rimegepant at outpatient clinics in the Greater Bay Area. It will assess the effectiveness of rimegepant in a real-world clinical setting, focusing on its impact on patients' quality of life, functioning, productivity, and overall satisfaction. The study will follow participants for four weeks to gather comprehensive data on their experiences and outcomes while using rimegepant.

Who should consider this trial

Good fit: Ideal candidates include adults over 18 years old with migraines as defined by the International Classification of Headache Disorders, who are prescribed rimegepant.

Not a fit: Patients with secondary headaches or those with severe impairments that prevent them from participating in the study may not benefit.

Why it matters

Potential benefit: If successful, this study could provide valuable insights into the real-world effectiveness of rimegepant for migraine treatment, potentially improving patient management strategies.

How similar studies have performed: While this study is observational, similar approaches have shown promise in evaluating real-world treatment effectiveness for migraines.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Participants with headaches that meet the diagnostic criteria for migraines according to the International Classification of Headache Disorders, 3rd edition (ICHD-3), with or without aura.
* Patients prescribed rimegepant by the attending physician for the treatment of migraines.
* Signed informed consent form.
* Age greater than 18 years.
* Not concurrently participating in other interventional clinical studies.

Exclusion Criteria:

* Patients diagnosed with secondary headaches.
* Patients with severe visual, auditory, language, intellectual, memory, consciousness impairments or other conditions that prevent them from completing the questionnaire and follow-up.
* Pregnant or lactating female patients.
* Patients deemed by the investigator as unsuitable for participation in the study or unable to complete the 4-week follow-up.
* Patients with a known history of hypersensitivity reactions to rimegepant or its components.
* Evidence in the medical history suggesting the presence of uncontrolled or unstable cardiovascular diseases (such as ischemic heart disease, coronary artery vasospasm, or cerebrovascular ischemia), or a history of myocardial infarction, acute coronary syndrome, percutaneous coronary intervention, cardiac surgery, stroke, or transient ischemic attack within the past 6 months before the screening visit.

Where this trial is running

Guangzhou, Guangdong

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Migraine
Last reviewed 2026-06-10 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.