Observing the effects of low flow anesthesia on waste gas emissions

The Effect of Two Different Fresh Gas Flows on Inhaled Gas Consumption During Wash-in Period in Patients Undergoing Low Flow Anesthesia: An Observational Study

Balikesir University · NCT06967948

This study is testing how different levels of gas flow during anesthesia affect the amount of waste gas released into the air and the costs of the anesthetic used, with volunteers aged 18 to 60 participating.

Quick facts

Study typeObservational
Enrollment40 (estimated)
Ages18 Years to 60 Years
SexAll
SponsorBalikesir University (other)
Drugs / interventionschemotherapy
Locations3 sites (Balıkesir and 2 other locations)
Trial IDNCT06967948 on ClinicalTrials.gov

What this trial studies

This observational study involves volunteers aged 18 to 60 who will undergo general anesthesia while their brain response to anesthetic agents and the concentration of inhaled anesthetics will be monitored. The researchers aim to evaluate the impact of different fresh gas flow rates (1 to 4 l/min) on the amount of waste gas released into the atmosphere and the associated costs of inhalation agents. By analyzing the relationship between gas flow rates and environmental impact, the study seeks to identify more sustainable anesthesia practices.

Who should consider this trial

Good fit: Ideal candidates are ASA I-II risk group patients undergoing surgeries lasting between 2 to 4 hours that require general anesthesia.

Not a fit: Patients with severe lung disease, significant cardiac issues, or those who have recently undergone chemotherapy or radiotherapy may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to reduced environmental impact and lower costs associated with inhalation anesthesia.

How similar studies have performed: While the approach of reducing fresh gas flow rates is established, the specific focus on environmental impact and cost reduction in this context is relatively novel.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* ASA I-II risk group patients Duration of surgery between 2 hours and 4 hours, cases with general anesthesia

Exclusion Criteria:

* Patient refusal to participate in the study
* Under 18 years old BMI\>40
* Patients receiving invasive mechanical ventilator support in the last 1 month
* Patients who have received chemotherapy or radiotherapy in the last 2 months
* Those with severe lung disease (COPD, asthma, pulmonary infection, bronchiectasis, previous need for non-invasive mechanical ventilation, oxygen therapy or steroid therapy for acute attack)
* Known severe pulmonary hypertension
* Smoke poisoning (carbon monoxide, cyanide poisoning)
* Alcohol or acetone poisoning
* Malignant hyperthermia
* Intracranial tumor
* Hemodynamic instability
* Shock
* Neuromuscular disease
* Pathologies causing increased intracranial and intraocular pressure
* Those with severe cardiac arrhythmias Those with -EF\<30
* Severe peripheral arterial disease
* Patients with liver and kidney dysfunction

Where this trial is running

Balıkesir and 2 other locations

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Inhalation Anesthesia

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.