Clinical trial Recruiting at 3 sites Observational Ages 18 to 60

Observing the effects of low flow anesthesia on waste gas emissions

Official title: The Effect of Two Different Fresh Gas Flows on Inhaled Gas Consumption During Wash-in Period in Patients Undergoing Low Flow Anesthesia: An Observational Study

Run by Balikesir University · NCT06967948 · Data updated 2026-11-12

This study is testing how different levels of gas flow during anesthesia affect the amount of waste gas released into the air and the costs of the anesthetic used, with volunteers aged 18 to 60 participating.

Quick facts

Study typeObservational
Ages18 Years to 60 Years
SexAll
Enrollment40 (estimated)
SponsorBalikesir University
Academic / other
Drugs / interventionschemotherapy
Locations3 sites (Balıkesir and 2 other locations)
StatusRecruiting
StartedApril 10, 2025
Main results expectedOctober 2025
Study endsDecember 2025
Registry record updatedMay 16, 2025
Trial IDNCT06967948 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are ASA I-II risk group patients undergoing surgeries lasting between 2 to 4 hours that require general anesthesia.

Probably not a fit

Patients with severe lung disease, significant cardiac issues, or those who have recently undergone chemotherapy or radiotherapy may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study involves volunteers aged 18 to 60 who will undergo general anesthesia while their brain response to anesthetic agents and the concentration of inhaled anesthetics will be monitored. The researchers aim to evaluate the impact of different fresh gas flow rates (1 to 4 l/min) on the amount of waste gas released into the atmosphere and the associated costs of inhalation agents. By analyzing the relationship between gas flow rates and environmental impact, the study seeks to identify more sustainable anesthesia practices.

Why it matters

Potential benefit: If successful, this study could lead to reduced environmental impact and lower costs associated with inhalation anesthesia.

How similar studies have gone: While the approach of reducing fresh gas flow rates is established, the specific focus on environmental impact and cost reduction in this context is relatively novel.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* ASA I-II risk group patients Duration of surgery between 2 hours and 4 hours, cases with general anesthesia

Exclusion Criteria:

* Patient refusal to participate in the study
* Under 18 years old BMI\>40
* Patients receiving invasive mechanical ventilator support in the last 1 month
* Patients who have received chemotherapy or radiotherapy in the last 2 months
* Those with severe lung disease (COPD, asthma, pulmonary infection, bronchiectasis, previous need for non-invasive mechanical ventilation, oxygen therapy or steroid therapy for acute attack)
* Known severe pulmonary hypertension
* Smoke poisoning (carbon monoxide, cyanide poisoning)
* Alcohol or acetone poisoning
* Malignant hyperthermia
* Intracranial tumor
* Hemodynamic instability
* Shock
* Neuromuscular disease
* Pathologies causing increased intracranial and intraocular pressure
* Those with severe cardiac arrhythmias Those with -EF\<30
* Severe peripheral arterial disease
* Patients with liver and kidney dysfunction

Where it's running

  • Balıkesir University Health Practice and Research Hospital Operating Room
    Balıkesir, Turkey (Türkiye)
    Recruiting
  • Balıkesir University Health Practice and Research Hospital
    Balıkesir, Turkey (Türkiye)
    Recruiting
  • Balıkesir University Health Practice and Research Hospital
    Balıkesir, Turkey (Türkiye)
    Recruiting

Study contacts

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.