Observing tendon damage in patients with osteogenesis imperfecta
Study of Osteogenesis Imperfecta Tendon and Ligament: Retrospective and Prospective Assessment.
This study looks at how tendon and ligament damage affects people with osteogenesis imperfecta to help improve their care and treatment options.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 130 (estimated) |
| Sex | All |
| Sponsor | Université Catholique de Louvain Academic / other |
| Locations | 1 site (Woluwe-Saint-Lambert, Brussels) |
| Trial ID | NCT06065111 on ClinicalTrials.gov |
What this trial studies
This observational study focuses on patients with osteogenesis imperfecta (OI), a genetic condition that leads to fragile bones and potential tendon damage. The research aims to assess the extent of tendon and ligament damage in these patients, correlating findings with previous experimental work conducted on a mouse model of OI. Data collected will help inform specific care strategies, particularly in physiotherapy, to alleviate pain and improve mobility. The study emphasizes the importance of understanding tendon-ligament pain to enhance treatment approaches for affected individuals.
Who should consider this trial
Good fit: Ideal candidates for this study are individuals diagnosed with osteogenesis imperfecta, regardless of age or specific type.
Not a fit: Patients without a diagnosis of osteogenesis imperfecta will not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved treatment strategies for managing tendon and ligament issues in patients with osteogenesis imperfecta.
How similar studies have performed: While there have been case reports on tendon ruptures in OI patients, this study represents a novel approach to systematically investigate tendon damage in this population.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * to have an osteogenesis imperfecta Exclusion Criteria: * none, since we want to study different types of osteogenesis imperfecta and consider the effect of age.
Where this trial is running
Woluwe-Saint-Lambert, Brussels
- Pole de Morphologie — Woluwe-Saint-Lambert, Brussels, Belgium (Recruiting)
Study contacts
- Principal investigator: Pierre-Louis Docquier, MD — Cliniques Univresitaires Saint-Luc
- Study coordinator: Catherine Behets
- Email: catherine.behets@uclouvain.be
- Phone: +3227645245
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.