Observing silent lumbar disc herniation in individuals without symptoms

Silent Lumbar Disc Herniation Syndrome

Observational Cairo University · NCT06453499

This study looks at people who have silent lumbar disc herniation but no symptoms to see how it affects their knee and ankle strength.

Quick facts

Study typeObservational
Enrollment180 (estimated)
Ages20 Years to 40 Years
SexAll
SponsorCairo University Academic / other
Locations1 site (Giza)
Trial IDNCT06453499 on ClinicalTrials.gov

What this trial studies

This observational study investigates silent lumbar disc herniation (LDH) in 180 individuals who do not exhibit any back or lower extremity symptoms. Participants will be categorized into three groups based on MRI findings: those with silent disc herniation and root compression, those with a history of disc herniation who have improved after physical therapy, and a control group without LDH. The study aims to assess the isokinetic peak torque of knee and ankle muscles and the H reflex to understand the biomechanical implications of silent LDH. The findings may help clinicians better screen for lower extremity injuries and guide treatment decisions.

Who should consider this trial

Good fit: Ideal candidates are individuals with lumbar disc herniation and root compression who do not have any back or lower extremity symptoms.

Not a fit: Patients with a history of lower extremity injuries, neuromuscular dysfunction, or any medical conditions affecting peripheral nerves may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could enhance understanding of silent lumbar disc herniation and improve screening and treatment strategies for lower extremity injuries.

How similar studies have performed: While the approach of observing asymptomatic individuals with disc herniation is less common, similar studies have shown potential in understanding the implications of silent conditions.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Inclusion criteria patients with LDH and root compression with no back or lower extremity symptoms.

Exclusion Criteria:

* Any previous history that would affect the alignment or the motion to lower extremity joints as fractures or surgery.

Any fixed deformity True leg length discrepancy (\>5mm). Any medical condition affecting peripheral nerves as diabetes mellitus. Any neuromuscular dysfunction and vestibular disorder.Sacroiliac pain or dysfunction low back pain.

Radicular or referred or radiating pain Previous lower extremity injury

Where this trial is running

Giza

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Disc Herniation
Last reviewed 2026-06-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.