Observing maternal and congenital infections of Toxoplasma
Lyon Clinical Research Program on Maternal and Congenital Toxoplasmosis Based on the Toxo-Ly Cohort: Risks and Clinical Consequences, Prevention, Diagnosis and Treatment
This study looks at pregnant women in France to see how Toxoplasma infections affect mothers and their babies, aiming to improve understanding and care for those impacted.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 4030 (estimated) |
| Sex | All |
| Sponsor | Hospices Civils de Lyon Academic / other |
| Locations | 1 site (Lyon) |
| Trial ID | NCT02936921 on ClinicalTrials.gov |
What this trial studies
This observational study focuses on the Lyon cohort of pregnant women to monitor and analyze maternal and congenital infections caused by Toxoplasma gondii. Since the implementation of a national prevention program in France, the study aims to systematically detect infections in mothers and their children, addressing questions regarding prognosis, diagnostic tests, treatment efficacy, and long-term management. The research is driven by the need for better understanding and guidance for clinicians and families affected by congenital toxoplasmosis.
Who should consider this trial
Good fit: Ideal candidates for this study are pregnant women confirmed to have a Toxoplasma infection during pregnancy or within 12 weeks prior to conception.
Not a fit: Patients whose maternal infections cannot be confirmed in the reference laboratory will not benefit from this study.
Why it matters
Potential benefit: If successful, this study could provide valuable insights into the management and treatment of congenital toxoplasmosis, improving outcomes for affected families.
How similar studies have performed: Other studies have shown success in monitoring and managing congenital infections, making this approach both relevant and necessary.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Confirmation in our laboratory of a maternal infection estimated to have occurred during pregnancy or during the 12 weeks preceding conception. Exclusion Criteria: * maternal :infection that could not be confirmed in our reference laboratory
Where this trial is running
Lyon
- Croix Rousse Hospital — Lyon, France (Recruiting)
Study contacts
- Study coordinator: Martine Wallon, PU PH
- Email: martine.wallon@chu-lyon.fr
- Phone: 4 72 07 18 72
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.