Observing lung health in early COPD patients
Lung Health of Early Chronic Obstructive Pulmonary Disease: A Multi-center Cohort Study
China-Japan Friendship Hospital · NCT05466396
This study looks at how lung health changes in people with early COPD and how smoking and other factors might affect that decline.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 1550 (estimated) |
| Ages | 35 Years to 75 Years |
| Sex | All |
| Sponsor | China-Japan Friendship Hospital (other) |
| Locations | 2 sites (Beijing, Beijing Municipality and 1 other locations) |
| Trial ID | NCT05466396 on ClinicalTrials.gov |
What this trial studies
This multi-center, prospective cohort study focuses on patients with early Chronic Obstructive Pulmonary Disease (COPD). It aims to investigate the decline in lung function and its relationship with smoking and other risk factors. The study will analyze various biomarkers and imaging results from chest CT scans to better understand lung health in these patients. By gathering data from multiple centers, the study seeks to provide a comprehensive view of early COPD progression.
Who should consider this trial
Good fit: Ideal candidates for this study are individuals aged 35-75 with early COPD characterized by specific spirometry results.
Not a fit: Patients with other significant lung diseases or conditions that could affect lung function may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved understanding and management of early COPD, potentially enhancing patient outcomes.
How similar studies have performed: While there have been studies on COPD, this specific approach focusing on early COPD and its risk factors is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. Gender: male or female 2. Age: 35-75 years old 3. post-bronchodilator spirometry: FEV1/FVC \< 0.8 and FEV1%pred ≥80% Exclusion Criteria: 1. Other diseases may affect lung function, like lung cancer, bronchiectasis, interstitial lung disease or chest surgery. 2. BMI \> 35 kg/m2 3. Dementia or other severe neurological disease 4. Pregnancy 5. Conditions that contraindicated lung function test
Where this trial is running
Beijing, Beijing Municipality and 1 other locations
- China-Japan Friendship Hospital — Beijing, Beijing Municipality, China (RECRUITING)
- Affiliated Hospital of Zunyi Medical University — Zunyi, Guizhou, China (RECRUITING)
Study contacts
- Principal investigator: Ting Yang, M.D. — China-Japan Friendship Hospital
- Study coordinator: Ke Huang, M.D.
- Email: huangke_zryy@163.com
- Phone: +86-010-84206276
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: COPD, early COPD, spirometry, lung health