Observing immune response and viral shedding in Oropouche virus infection
OBSERVATIONAL STUDY ON VIRAL SHEDDING AND IMMUNOLOGICAL RESPONSE OF OROPOUCHE VIRUS
This study looks at how the immune system reacts and how long the Oropouche virus stays in the body of people who have tested positive for it.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 30 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | IRCCS Sacro Cuore Don Calabria di Negrar Academic / other |
| Locations | 1 site (Negrar, VR) |
| Trial ID | NCT06892015 on ClinicalTrials.gov |
What this trial studies
This observational study aims to describe the immune response to Oropouche Virus (OROV) and the duration of viral RNA shedding in patients. It involves both retrospective and prospective enrollment of participants who have tested positive for OROV through RT-PCR. Sequential samples will be collected and analyzed using RT-PCR across different biological matrices to gather comprehensive data on the viral shedding process and immune response over time.
Who should consider this trial
Good fit: Ideal candidates for this study are adults aged 18 and older who have tested positive for Oropouche virus.
Not a fit: Patients who do not provide informed consent or those who have not tested positive for Oropouche virus will not benefit from this study.
Why it matters
Potential benefit: If successful, this study could enhance understanding of Oropouche virus infection, leading to improved management and treatment strategies for affected patients.
How similar studies have performed: While there may be limited studies specifically on Oropouche virus, similar observational studies on viral infections have shown success in understanding immune responses and viral dynamics.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * patients resulted positive to the RT-PCR for OROV; * informed consent to the participation to the study and to personal data's treatment and/or donation of residual samples to Tropika Biobank; * patients ≥ 18 years old. Exclusion Criteria • lack of signed informed consent.
Where this trial is running
Negrar, VR
- IRCCS Sacro Cuore Don Calabria — Negrar, Vr, Italy (Recruiting)
Study contacts
- Study coordinator: Elvia Malo
- Email: ricerca.clinica@sacrocuore.it
- Phone: +390456013111
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.