Observing eye complications in patients with monkeypox in the Democratic Republic of Congo
Mapping the Burden of Ocular Complications of Mpox in the Democratic Republic Congo (DRC)
Institute of Tropical Medicine, Belgium · NCT06579885
This study looks at eye problems in people with monkeypox in the Democratic Republic of Congo to see how the virus might affect their vision.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 62 (estimated) |
| Sex | All |
| Sponsor | Institute of Tropical Medicine, Belgium (other) |
| Locations | 1 site (Kamituga, South-Kivu Province) |
| Trial ID | NCT06579885 on ClinicalTrials.gov |
What this trial studies
This observational study enrolls patients diagnosed with monkeypox in two clinics in remote areas of the Democratic Republic of Congo. Participants will undergo standard ophthalmological examinations to assess any eye complications associated with monkeypox. The study includes various assessments such as history taking, clinical examinations, and technical tests to detect the presence of the monkeypox virus in tears. Follow-up visits will occur at specified intervals to monitor any new or worsening symptoms. Participants will receive supportive eye care and compensation for their time and travel.
Who should consider this trial
Good fit: Ideal candidates include individuals of any age or gender with a laboratory-confirmed monkeypox infection within the last 48 hours.
Not a fit: Patients whose participation may interfere with optimal clinical care will not benefit from this study.
Why it matters
Potential benefit: If successful, this study could enhance understanding of the ocular complications associated with monkeypox, leading to better patient management.
How similar studies have performed: While there is limited data on similar studies, the approach of assessing complications in infectious diseases is common, though this specific focus on monkeypox is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patient of any age or gender with laboratory-confirmed infection with MPXV * Laboratory confirmation of MPXV infection less than 48 hours before inclusion * Patient or culturally acceptable representative is willing and able to give informed consent or assent for participation in the study Exclusion Criteria: * Patients for whom, in the judgment of the recruiting physician, participation in the study would interfere with routine optimal clinical care.
Where this trial is running
Kamituga, South-Kivu Province
- Kamituga General Hospital — Kamituga, South-Kivu Province, Congo, The Democratic Republic of the (RECRUITING)
Study contacts
- Study coordinator: Placide Mbala Kingebeni, Professor
- Email: mbalaplacide@gmail.com
- Phone: +243822851584
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Monkeypox, Mpox, ophthalmology, complications