Observing decongestion in heart failure patients
Description and Analysis of Congestion During Hospitalization for Acute Decompensated Heart Failure
This study looks at how to help people with acute heart failure feel less congested while they're in the hospital and tracks their health for a year after they go home.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 300 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | University of Chile Academic / other |
| Locations | 1 site (Santiago, Metropolitan) |
| Trial ID | NCT06244693 on ClinicalTrials.gov |
What this trial studies
This observational study aims to understand the decongestion process in patients hospitalized for acute heart failure. It will evaluate clinical, analytical, and ultrasonographic variables related to congestion during hospitalization. Participants will be followed for one year post-discharge to assess mortality and rehospitalization rates. The study is conducted at the Clinical Hospital of the University of Chile, focusing on optimizing management for heart failure patients.
Who should consider this trial
Good fit: Ideal candidates include adults diagnosed with decompensated heart failure who are hospitalized at the Clinical Hospital of the University of Chile.
Not a fit: Patients with dry-type heart failure profiles or those with conditions mimicking heart failure may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could improve the management and outcomes of heart failure patients by providing insights into effective decongestion strategies.
How similar studies have performed: Other studies have shown success in understanding heart failure management, but this specific observational approach is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Adults diagnosed with decompensated heart failure in the emergency department or cardiology outpatient clinic at the Clinical Hospital of the University of Chile (HCUCh). * Profile of warm-wet and cold-wet type heart failure. * Spontaneous ventilation with or without non-invasive mechanical support. * Desire for participation validated through informed consent. Exclusion Criteria: * Dry-type heart failure profile (warm and cold) * Diagnostics that mimics heart failure (valvular heart disease, cardiomyopathies, and others diagnostic different from heart failure). * Septic, distributive, or obstructive shock * Polytraumatized * Severe burns * Invasive mechanical ventilation * Permanent renal replacement therapy * Severe dependence * Presence of terminal illness with a prognosis of survival less than one year * Presence of traumatic conditions that prevent the use of thoracic ultrasound, such as a flail chest or moderate to severe burn on the left hemithorax. * Lack of a support network or contact. * Cardiorespiratory arrest * Refusal to participate as indicated in the informed consent. * Presence of psychological or intellectual disability that prevents expressing the will to participate.
Where this trial is running
Santiago, Metropolitan
- Departamento Cardiovascular - Hospital Clínico Universidad de Chile — Santiago, Metropolitan, Chile (Recruiting)
Study contacts
- Principal investigator: Alfredo Parra, MD,PhD — Departamento Cardiovascular - Hospital Clínico Universidad de Chile
- Study coordinator: Alfredo Parra, MD, PhD
- Email: alfredop@uchile.cl
- Phone: 229788326
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.