Observing cough patterns in patients with chronic cough

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to characterize different cough phenotypes in patients suffering from chronic cough by utilizing a novel questionnaire. The study involves two parts: an initial screening followed by the completion of the questionnaire, which assesses cough patterns, frequency, intensity, and the impact on daily life. Participants will complete the questionnaire twice, with a follow-up 2-4 weeks later to track any changes. The study seeks to better understand how patients perceive their cough severity and its disruption to their lives.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. Male and female patients \> 18yrs of age
2. Patients with a current cough of at least 8 weeks duration
3. Patients with a clear chest X-Ray within previous 2 yrs
4. Non- smoker
5. Able to understand and comply with the requirements of the study and sign Informed Consent forms.
6. Good understanding of written and spoken English -

Exclusion Criteria:

1. Recent respiratory tract infection (\<4 weeks prior).
2. Current smokers or ex-smokers with \<6 months' abstinence prior to Study.
3. Any clinically significant or unstable medical or psychiatric condition that would, in the opinion of the investigator, interfere with the subject's ability to participate in the study safely.
4. Participation in any clinical research study evaluating an investigational drug or therapy within 30 days or within 5 half-lives (whichever is longer) of the investigational drug prior to Study visit. If the subject was in an observational clinical study no washout is required.
5. Subjects who, in the opinion of the Investigator, should not participate in the study for any other reason.

Where it's running

• Redspiratory Medicine, First Floor, Daisy Building, Castle Hill Hospital
  Cottingham, East Yorkshiure, United Kingdom Recruiting

Study contacts

• Study coordinator: Caroline Wright, BSc
• Email: c.wright@hull.ac.uk
• Phone: 01482624067

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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• Behavioral therapy for persistent chronic cough

  This program will try behavioral cough suppression therapy to help adults whose cough has lasted more than eight weeks and has not improved with usual treatments.

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• Biomarkers and Respiratory Omics in Children: Predicting Disease Course

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• Evaluating treatment satisfaction with gefapixant for chronic cough

  This study is testing how satisfied adults with stubborn chronic cough are with the treatment gefapixant and whether any taste changes they experience affect their quality of life related to coughing.

  Recruiting Nagoya City University · Nagoya, Aichi-ken and 1 other locations · NCT06542484

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.