Observing cough patterns in patients with chronic cough
An Observational Study Using Novel Questionnaire to Characterize Cough Phenotypes in Patients With Chronic Cough
This study is trying to understand different types of coughs in people with chronic cough by using a new questionnaire to see how often they cough and how it affects their daily life.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 60 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Hull University Teaching Hospitals NHS Trust Government |
| Locations | 1 site (Cottingham, East Yorkshiure) |
| Trial ID | NCT06376448 on ClinicalTrials.gov |
What this trial studies
This observational study aims to characterize different cough phenotypes in patients suffering from chronic cough by utilizing a novel questionnaire. The study involves two parts: an initial screening followed by the completion of the questionnaire, which assesses cough patterns, frequency, intensity, and the impact on daily life. Participants will complete the questionnaire twice, with a follow-up 2-4 weeks later to track any changes. The study seeks to better understand how patients perceive their cough severity and its disruption to their lives.
Who should consider this trial
Good fit: Ideal candidates are adults over 18 years with a chronic cough lasting at least 8 weeks and a clear chest X-ray within the last two years.
Not a fit: Patients with recent respiratory infections, current smokers, or those with unstable medical conditions may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved understanding and management of chronic cough, enhancing patient care.
How similar studies have performed: While the approach of characterizing cough patterns is novel, similar observational studies have shown promise in understanding other chronic symptoms.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. Male and female patients \> 18yrs of age 2. Patients with a current cough of at least 8 weeks duration 3. Patients with a clear chest X-Ray within previous 2 yrs 4. Non- smoker 5. Able to understand and comply with the requirements of the study and sign Informed Consent forms. 6. Good understanding of written and spoken English - Exclusion Criteria: 1. Recent respiratory tract infection (\<4 weeks prior). 2. Current smokers or ex-smokers with \<6 months' abstinence prior to Study. 3. Any clinically significant or unstable medical or psychiatric condition that would, in the opinion of the investigator, interfere with the subject's ability to participate in the study safely. 4. Participation in any clinical research study evaluating an investigational drug or therapy within 30 days or within 5 half-lives (whichever is longer) of the investigational drug prior to Study visit. If the subject was in an observational clinical study no washout is required. 5. Subjects who, in the opinion of the Investigator, should not participate in the study for any other reason.
Where this trial is running
Cottingham, East Yorkshiure
- Redspiratory Medicine, First Floor, Daisy Building, Castle Hill Hospital — Cottingham, East Yorkshiure, United Kingdom (Recruiting)
Study contacts
- Study coordinator: Caroline Wright, BSc
- Email: c.wright@hull.ac.uk
- Phone: 01482624067
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.