Clinical trial Recruiting at 1 site Observational Ages 18 to 85

Observing coronary microvascular disease in patients

Official title: China Coronary Microvascular Disease(CCMD) Registry

Run by Henan Institute of Cardiovascular Epidemiology · NCT06676137 · Data updated 2026-11-12

This study looks at patients with coronary microvascular disease to see how the condition develops and affects their quality of life and heart health.

Quick facts

Study typeObservational
Ages18 Years to 85 Years
SexAll
Enrollment500 (estimated)
SponsorHenan Institute of Cardiovascular Epidemiology
Academic / other
Locations1 site (Zhengzhou)
StatusRecruiting
StartedNovember 11, 2024
Main results expectedOctober 10, 2028
Study endsOctober 10, 2029
Registry record updatedAugust 20, 2025
Trial IDNCT06676137 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are adults experiencing angina symptoms with objective evidence of myocardial ischemia and normal coronary angiography.

Probably not a fit

Patients under 18 years old or those with non-cardiogenic chest pain or other specific heart conditions will not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study focuses on patients diagnosed with coronary microvascular disease (CMD), a type of non-obstructive coronary heart disease characterized by angina pectoris without significant narrowing of the epicardial vessels. The study aims to prospectively collect data on these patients to observe the disease's development and outcomes, while also exploring the mechanisms behind its occurrence. By gathering clinical evidence, the study seeks to enhance understanding of CMD and its impact on patient quality of life and cardiovascular risks.

Why it matters

Potential benefit: If successful, this study could lead to improved understanding and management of coronary microvascular disease, potentially enhancing patient outcomes.

How similar studies have gone: While the study addresses a growing concern in cardiovascular health, similar observational studies have shown varying degrees of success in understanding CMD, indicating both potential and the need for further exploration.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

1. Angina symptoms
2. Objective evidence of myocardial ischemia
3. Coronary angiography was normal,irregular tube wall, or stenosis \<50%

Exclusion Criteria:

1. People under the age of 18
2. Non-cardiogenic chest pain and other heart conditions such as variant angina, cardiomyopathy, myocarditis or valvular heart disease

Where it's running

  • Fuwai central China cardiovascular hospotial
    Zhengzhou, China
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.