Observing coronary microvascular disease in patients

China Coronary Microvascular Disease(CCMD) Registry

Henan Institute of Cardiovascular Epidemiology · NCT06676137

This study looks at patients with coronary microvascular disease to see how the condition develops and affects their quality of life and heart health.

Quick facts

Study typeObservational
Enrollment500 (estimated)
Ages18 Years to 85 Years
SexAll
SponsorHenan Institute of Cardiovascular Epidemiology (other)
Locations1 site (Zhengzhou)
Trial IDNCT06676137 on ClinicalTrials.gov

What this trial studies

This observational study focuses on patients diagnosed with coronary microvascular disease (CMD), a type of non-obstructive coronary heart disease characterized by angina pectoris without significant narrowing of the epicardial vessels. The study aims to prospectively collect data on these patients to observe the disease's development and outcomes, while also exploring the mechanisms behind its occurrence. By gathering clinical evidence, the study seeks to enhance understanding of CMD and its impact on patient quality of life and cardiovascular risks.

Who should consider this trial

Good fit: Ideal candidates for this study are adults experiencing angina symptoms with objective evidence of myocardial ischemia and normal coronary angiography.

Not a fit: Patients under 18 years old or those with non-cardiogenic chest pain or other specific heart conditions will not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to improved understanding and management of coronary microvascular disease, potentially enhancing patient outcomes.

How similar studies have performed: While the study addresses a growing concern in cardiovascular health, similar observational studies have shown varying degrees of success in understanding CMD, indicating both potential and the need for further exploration.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

1. Angina symptoms
2. Objective evidence of myocardial ischemia
3. Coronary angiography was normal,irregular tube wall, or stenosis \<50%

Exclusion Criteria:

1. People under the age of 18
2. Non-cardiogenic chest pain and other heart conditions such as variant angina, cardiomyopathy, myocarditis or valvular heart disease

Where this trial is running

Zhengzhou

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Coronary Microvascular Disease

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.