Observing coronary microvascular disease in patients
Official title: China Coronary Microvascular Disease(CCMD) Registry
Run by Henan Institute of Cardiovascular Epidemiology · NCT06676137 · Data updated 2026-11-12
This study looks at patients with coronary microvascular disease to see how the condition develops and affects their quality of life and heart health.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years to 85 Years |
| Sex | All |
| Enrollment | 500 (estimated) |
| Sponsor | Henan Institute of Cardiovascular Epidemiology Academic / other |
| Locations | 1 site (Zhengzhou) |
| Status | Recruiting |
| Started | November 11, 2024 |
| Main results expected | October 10, 2028 |
| Study ends | October 10, 2029 |
| Registry record updated | August 20, 2025 |
| Trial ID | NCT06676137 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are adults experiencing angina symptoms with objective evidence of myocardial ischemia and normal coronary angiography.
✕Probably not a fit
Patients under 18 years old or those with non-cardiogenic chest pain or other specific heart conditions will not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study focuses on patients diagnosed with coronary microvascular disease (CMD), a type of non-obstructive coronary heart disease characterized by angina pectoris without significant narrowing of the epicardial vessels. The study aims to prospectively collect data on these patients to observe the disease's development and outcomes, while also exploring the mechanisms behind its occurrence. By gathering clinical evidence, the study seeks to enhance understanding of CMD and its impact on patient quality of life and cardiovascular risks.
Why it matters
Potential benefit: If successful, this study could lead to improved understanding and management of coronary microvascular disease, potentially enhancing patient outcomes.
How similar studies have gone: While the study addresses a growing concern in cardiovascular health, similar observational studies have shown varying degrees of success in understanding CMD, indicating both potential and the need for further exploration.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. Angina symptoms 2. Objective evidence of myocardial ischemia 3. Coronary angiography was normal,irregular tube wall, or stenosis \<50% Exclusion Criteria: 1. People under the age of 18 2. Non-cardiogenic chest pain and other heart conditions such as variant angina, cardiomyopathy, myocarditis or valvular heart disease
Where it's running
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Fuwai central China cardiovascular hospotial
Zhengzhou, China Recruiting
Study contacts
- Study coordinator: Quan Guo
- Email: xinyiguoquan@163.com
- Phone: +8615670510031
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
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Qishenyiqi Dripping Pill for treating Coronary Microvascular Disease
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This trial will test whether taking the SGLT2 pill Brezavvy for 12 weeks can improve coronary microvascular blood flow and reduce angina symptoms in women with non-obstructive coronary artery disease.
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Registry collecting data on microvascular dysfunction and coronary spasm
This study is collecting information from patients with microvascular dysfunction and coronary spasm to better understand their experiences and improve their care.
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This study is testing how well people with heart conditions, especially those with coronary artery disease, can handle fast heart rates and whether treating their condition with stents can help them tolerate it better.
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.