Observing corneal opacities in adults
Observational Study of Corneal Opacities in Adults
Oregon Health and Science University · NCT02109471
This study is looking at adults with corneal scars and dystrophies to see how deep the opacities are and how they affect the cornea using advanced imaging techniques.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 150 (estimated) |
| Ages | 18 Years to 100 Years |
| Sex | All |
| Sponsor | Oregon Health and Science University (other) |
| Locations | 1 site (Portland, Oregon) |
| Trial ID | NCT02109471 on ClinicalTrials.gov |
What this trial studies
This observational study focuses on adults with corneal opacities, specifically scar and stromal dystrophy, at Oregon Health and Science University. It involves 150 participants who will undergo 3-D corneal scans using the Optovue anterior segment OCT to assess opacity depth, corneal thickness, and topography. Additional imaging techniques, including Placido-ring corneal topography and ultrasound pachymetry, will be utilized for comprehensive evaluation and comparison. The study aims to gather detailed data on corneal conditions to enhance understanding and treatment approaches.
Who should consider this trial
Good fit: Ideal candidates are adults aged 18 and older presenting with corneal opacities at the OHSU Casey Eye Clinic.
Not a fit: Patients unable to provide informed consent or maintain stable fixation for imaging may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved diagnostic techniques and treatment strategies for patients with corneal opacities.
How similar studies have performed: While this study employs established imaging techniques, the specific focus on corneal opacities in this manner may provide novel insights, as similar studies have shown varying degrees of success.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: • Adult (18 \& older) patients presenting in OHSU Casey Eye Clinic with corneal opacities (scar and stromal dystrophy) Exclusion Criteria: * Inability to give informed consent. * Inability to maintain stable fixation for OCT imaging. * Inability to commit to required visits to complete the study.
Where this trial is running
Portland, Oregon
- Humberto Martinez — Portland, Oregon, United States (RECRUITING)
Study contacts
- Principal investigator: David Huang, MD, PhD — Oregon Health and Science University
- Study coordinator: Humberto Martinez, COT
- Email: martinhu@ohsu.edu
- Phone: 503-494-7712
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Corneal Opacities, corneal opacities, Optical coherence tomography