Observing chronic pain in children after surgery

Child and Parent Emotion-related Risk and Resilience Factors Associated With the Transition From Acute to Chronic Pain After Surgery: A Prospective Longitudinal Study

Observational University Children's Hospital, Zurich · NCT05816174

This study looks at how emotions affect chronic pain in children and teens after they have major orthopedic surgery to help improve pain management for young patients.

Quick facts

Study typeObservational
Enrollment281 (estimated)
Ages8 Years to 18 Years
SexAll
SponsorUniversity Children's Hospital, Zurich Academic / other
Locations3 sites (Basel and 2 other locations)
Trial IDNCT05816174 on ClinicalTrials.gov

What this trial studies

This observational study aims to investigate the development and maintenance of chronic postsurgical pain in children and adolescents following major orthopedic surgery. It will assess emotion-related factors at five different time points: one before surgery and four after. By examining how emotions are regulated and differentiated, the study seeks to identify risk factors that may contribute to chronic pain. The findings could provide insights into improving pain management strategies for young patients.

Who should consider this trial

Good fit: Ideal candidates for this study are children and adolescents aged 8 to 18 years who are scheduled for major orthopedic surgery requiring inpatient care.

Not a fit: Patients with serious comorbid health conditions or those who have undergone prior major orthopedic surgery may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to better understanding and management of chronic postsurgical pain in children, ultimately improving their quality of life.

How similar studies have performed: While emotion-related factors have been studied in other types of chronic pain, this specific approach to chronic postsurgical pain in children is novel and has not been previously examined.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Children and adolescents aged between 8 and 18 years
* Planned orthopedic surgery requiring in-patient care in one of the participating children's hospitals
* Able to read and understand German

Exclusion Criteria:

* Serious comorbid health condition (e.g., cancer, severe neurological impairment, chronic illness requiring daily medication)
* Prior major orthopedic surgery (e.g., prior spine surgery)
* Parent/caregiver and child not able to read and understand German

Where this trial is running

Basel and 2 other locations

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Chronic Post Operative Pain
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.