Observing changes in pediatric cataract treatment and recovery
The Cohort Study of Pediatric Cataract
This study looks at how different treatments for cataracts in young children affect their vision and recovery, while also checking their emotional and mental well-being.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 5000 (estimated) |
| Ages | N/A to 18 Years |
| Sex | All |
| Sponsor | Zhongshan Ophthalmic Center, Sun Yat-sen University Academic / other |
| Locations | 1 site (Guangzhou, Guangdong) |
| Trial ID | NCT05472844 on ClinicalTrials.gov |
What this trial studies
This observational cohort study focuses on young children with cataracts, aiming to analyze changes in ocular parameters and the effectiveness of various surgical and vision recovery strategies. It will compare outcomes before and after cataract surgery, while also considering psychological and cognitive impacts. Blood samples from participants and their parents will be collected for genetic analysis, and tissue samples will be taken during surgery for further research. The study employs advanced artificial intelligence techniques to enhance diagnosis and treatment planning.
Who should consider this trial
Good fit: Ideal candidates are children under 18 years old with unilateral or bilateral cataracts who consent to participate.
Not a fit: Adults and those who do not have cataracts will not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved treatment strategies and better recovery outcomes for children with cataracts.
How similar studies have performed: While there have been studies on pediatric cataracts, this approach combining genetic analysis and AI for treatment optimization is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * aged \< 18 yo at the 1st visit unilateral or bilateral cataract agree to participant in this study and sign the informed consent Exclusion Criteria: * adults
Where this trial is running
Guangzhou, Guangdong
- Zhongshan Ophthalmic Center — Guangzhou, Guangdong, China (Recruiting)
Study contacts
- Principal investigator: Yizhi Liu, PhD — Zhongshan Ophthalmic Center, Sun Yat-sen University
- Study coordinator: Zhenzhen Liu, PhD
- Email: liuzhenzhen@gzzoc.com
- Phone: +020 66618932
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.