Clinical trial Recruiting at 1 site Observational Ages Any age to 18

Observing changes in pediatric cataract treatment and recovery

Official title: The Cohort Study of Pediatric Cataract

Run by Zhongshan Ophthalmic Center, Sun Yat-sen University · NCT05472844 · Data updated 2026-11-12

This study looks at how different treatments for cataracts in young children affect their vision and recovery, while also checking their emotional and mental well-being.

Quick facts

Study typeObservational
AgesAny age to 18 Years
SexAll
Enrollment5000 (estimated)
SponsorZhongshan Ophthalmic Center, Sun Yat-sen University
Academic / other
Locations1 site (Guangzhou, Guangdong)
StatusRecruiting
StartedAugust 22, 2022
Main results expectedJanuary 1, 2032
Study endsFebruary 1, 2032
Registry record updatedSeptember 27, 2022
Trial IDNCT05472844 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are children under 18 years old with unilateral or bilateral cataracts who consent to participate.

Probably not a fit

Adults and those who do not have cataracts will not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational cohort study focuses on young children with cataracts, aiming to analyze changes in ocular parameters and the effectiveness of various surgical and vision recovery strategies. It will compare outcomes before and after cataract surgery, while also considering psychological and cognitive impacts. Blood samples from participants and their parents will be collected for genetic analysis, and tissue samples will be taken during surgery for further research. The study employs advanced artificial intelligence techniques to enhance diagnosis and treatment planning.

Why it matters

Potential benefit: If successful, this study could lead to improved treatment strategies and better recovery outcomes for children with cataracts.

How similar studies have gone: While there have been studies on pediatric cataracts, this approach combining genetic analysis and AI for treatment optimization is relatively novel.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* aged \< 18 yo at the 1st visit unilateral or bilateral cataract agree to participant in this study and sign the informed consent

Exclusion Criteria:

* adults

Where it's running

  • Zhongshan Ophthalmic Center
    Guangzhou, Guangdong, China
    Recruiting

Study contacts

  • Principal investigator: Yizhi Liu, PhD — Zhongshan Ophthalmic Center, Sun Yat-sen University
  • Study coordinator: Zhenzhen Liu, PhD
  • Email: liuzhenzhen@gzzoc.com
  • Phone: +020 66618932

Similar studies

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.