Observing changes in pediatric cataract treatment and recovery
Official title: The Cohort Study of Pediatric Cataract
Run by Zhongshan Ophthalmic Center, Sun Yat-sen University · NCT05472844 · Data updated 2026-11-12
This study looks at how different treatments for cataracts in young children affect their vision and recovery, while also checking their emotional and mental well-being.
Quick facts
| Study type | Observational |
|---|---|
| Ages | Any age to 18 Years |
| Sex | All |
| Enrollment | 5000 (estimated) |
| Sponsor | Zhongshan Ophthalmic Center, Sun Yat-sen University Academic / other |
| Locations | 1 site (Guangzhou, Guangdong) |
| Status | Recruiting |
| Started | August 22, 2022 |
| Main results expected | January 1, 2032 |
| Study ends | February 1, 2032 |
| Registry record updated | September 27, 2022 |
| Trial ID | NCT05472844 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are children under 18 years old with unilateral or bilateral cataracts who consent to participate.
✕Probably not a fit
Adults and those who do not have cataracts will not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational cohort study focuses on young children with cataracts, aiming to analyze changes in ocular parameters and the effectiveness of various surgical and vision recovery strategies. It will compare outcomes before and after cataract surgery, while also considering psychological and cognitive impacts. Blood samples from participants and their parents will be collected for genetic analysis, and tissue samples will be taken during surgery for further research. The study employs advanced artificial intelligence techniques to enhance diagnosis and treatment planning.
Why it matters
Potential benefit: If successful, this study could lead to improved treatment strategies and better recovery outcomes for children with cataracts.
How similar studies have gone: While there have been studies on pediatric cataracts, this approach combining genetic analysis and AI for treatment optimization is relatively novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * aged \< 18 yo at the 1st visit unilateral or bilateral cataract agree to participant in this study and sign the informed consent Exclusion Criteria: * adults
Where it's running
-
Zhongshan Ophthalmic Center
Guangzhou, Guangdong, China Recruiting
Study contacts
- Principal investigator: Yizhi Liu, PhD — Zhongshan Ophthalmic Center, Sun Yat-sen University
- Study coordinator: Zhenzhen Liu, PhD
- Email: liuzhenzhen@gzzoc.com
- Phone: +020 66618932
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.