Observing bone loss in implant-retained dentures
Ten Years Retrospective Study of 4 LOCATOR Attachment of Mandibular Implant Retained Overdenture With 2 Different Distributions.
This study looks at how well implant-retained dentures help prevent bone loss in patients who have trouble with denture stability.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 20 (estimated) |
| Ages | 55 Years to 80 Years |
| Sex | All |
| Sponsor | Mansoura University Academic / other |
| Drugs / interventions | chemotherapy, radiation |
| Locations | 1 site (Multiple Locations) |
| Trial ID | NCT05910333 on ClinicalTrials.gov |
What this trial studies
This observational study aims to assess the degree of crestal bone loss around four inter-foraminal implant-retained mandibular overdentures (OVDs) and the associated bone remodeling in the anterior maxilla and posterior mandible over the long term. It focuses on patients who have experienced issues with denture retention and stability, particularly those treated in a Master's program in Prosthodontics. The study will utilize LOCATOR attachments, which offer dual retention and self-aligning features, to evaluate their effectiveness in maintaining bone health and denture function.
Who should consider this trial
Good fit: Ideal candidates include edentulous patients with four implants in the inter-foraminal region and specific bone height requirements.
Not a fit: Patients with contraindications such as significant smoking, alcoholism, or a history of head and neck radiation therapy may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could provide valuable insights into improving the longevity and effectiveness of implant-retained dentures for edentulous patients.
How similar studies have performed: While there is existing literature on implant retention, this specific approach to observing long-term bone loss with four implants is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients with 4 implants in the inter-foraminal region. * Patients treated by staff and students in the Master's program in Prosthodontics Department according to the following criteria: * Edentulous maxilla and mandible for at least 1 year. * Problems with retention and stability of the mandibular denture. * Mandibular bone height between 15 and 25 mm. Exclusion Criteria: * Patients with relative contraindications, such as * A history of para functional habits. * Smokers more than 10 cigarettes per day. * alcoholism. * Patients with a history of radiation therapy in the head and neck region . • Patients within intravenous administrated bisphosphonates., chemotherapy, and mental disorders that could jeopardies their co-operation.
Where this trial is running
Multiple Locations
- Mohammed El Sawy — Multiple Locations, Egypt (Recruiting)
Study contacts
- Study coordinator: Mohammed E Sawy, PhD
- Email: Dr_sawy@windowslive.com
- Phone: +201061314522
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.