Observing Barrett's Esophagus with Dysplasia and Early Cancer
Official title: Australian Barrett's Cohort With Dysplasia and Early Cancer Study
Run by Western Sydney Local Health District · NCT02198976 · Data updated 2026-11-12
This study looks at how patients with Barrett's esophagus, especially those with serious changes or early cancer, are managed over time to see how their condition progresses and how well treatments work.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years to 99 Years |
| Sex | All |
| Enrollment | 300 (estimated) |
| Sponsor | Western Sydney Local Health District Academic / other |
| Locations | 1 site (Westmead, New South Wales) |
| Status | Recruiting |
| Started | April 2014 |
| Main results expected | May 2034 |
| Study ends | November 2034 |
| Registry record updated | March 27, 2025 |
| Trial ID | NCT02198976 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are adults over 18 years old diagnosed with Barrett's esophagus.
✕Probably not a fit
Patients under 18 years old or those who are pregnant will not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study aims to collect observational data on the management and outcomes of patients with Barrett's esophagus who have high-grade dysplasia or intramucosal carcinoma. It also seeks to understand the natural history of patients with low-grade dysplastic and non-dysplastic Barrett's esophagus. By monitoring these patients over time, the study will provide insights into disease progression and treatment effectiveness.
Why it matters
Potential benefit: If successful, this study could improve the management and treatment strategies for patients with Barrett's esophagus, potentially leading to better outcomes.
How similar studies have gone: While observational studies on Barrett's esophagus exist, this specific cohort approach focusing on dysplasia and early cancer is relatively novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Can give informed consent to trial participation * Age greater than 18 * Barrett's oesophagus Exclusion Criteria: * Age less than 18 * Pregnant patients
Where it's running
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Westmead Endoscopy Unit
Westmead, New South Wales, Australia Recruiting
Study contacts
- Principal investigator: Michael J Bourke, MBBS — Western Sydney Local Health District
- Study coordinator: Michael Bourke, MBBS
- Email: michael@citywestgastro.com.au
- Phone: 88905555
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
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Using a capsule system to detect Barrett's Esophagus
This study is testing a new capsule system to see if it can help find Barrett's Esophagus in adults who have had an endoscopy recently.
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Using tissue, brush, and blood tests to improve cancer risk prediction and quality of life tracking in Barrett's Esophagus
This will try extra biopsies, esophageal brushings, blood tests, and short questionnaires to see if they can better predict cancer risk and track quality of life for adults with Barrett's Esophagus who are being evaluated for possible early cancer.
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Investigating the best biopsy methods for Barrett's Esophagus
This study is testing different biopsy methods to see which one works best for finding early signs of Barrett's Esophagus in patients, especially in Asian populations.
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Testing a new imaging capsule for Barrett's Esophagus
This study is testing a new imaging capsule to see if it can safely and easily take pictures of the esophagus in both healthy people and those with Barrett's Esophagus.
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Treatment options for Barrett's Esophagus and related cancer
This study is looking at how well different treatments work for people with Barrett's esophagus and esophageal cancer to help improve their health and quality of life.
-
Project to improve detection of Barrett's Esophagus and related neoplasia
This study is testing new ways to better detect Barrett's esophagus and early signs of cancer to help improve care for patients with this condition.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.