Observational study on vascular liver diseases
Vienna Vascular Liver Disease Study: Characterization of Patients With Vascular Liver Disease - a Registry With Biobank
Medical University of Vienna · NCT03541057
This study looks at the causes and effects of different vascular liver diseases to see how they impact patients and what new tests might help in their treatment.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 200 (estimated) |
| Ages | 18 Years to 100 Years |
| Sex | All |
| Sponsor | Medical University of Vienna (other) |
| Locations | 1 site (Vienna) |
| Trial ID | NCT03541057 on ClinicalTrials.gov |
What this trial studies
This observational study aims to systematically investigate the epidemiology, risk factors, liver function, and prognosis of patients with various vascular liver diseases, including portal vein thrombosis and Budd-Chiari syndrome. It will assess important clinical parameters to evaluate patients' coagulation status and develop new biomarkers from blood, urine, stool, or ascites, as well as histological samples. The study will also track the natural history of these conditions, focusing on hepatic decompensation and the need for intensified treatment.
Who should consider this trial
Good fit: Ideal candidates include adults aged 18 to 100 diagnosed with vascular liver diseases such as portal vein thrombosis or Budd-Chiari syndrome.
Not a fit: Patients who do not have a diagnosis of vascular liver disease or are unwilling to provide informed consent may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved understanding and management of vascular liver diseases, potentially enhancing patient outcomes.
How similar studies have performed: While this study focuses on a specific cohort of vascular liver diseases, similar observational studies have shown success in understanding complex liver conditions and their management.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Diagnosis of a vascular liver disease by imaging (sonography, CT, MRI), transient elastography or liver histology * PVT: Portal vein thrombosis * NCPH: non-cirrhotic Portal Hypertension * PSVD: porto-sinusoidal vascular disorder * BCS: Budd-Chiari-Syndrome * SOS: sinusoidal occlusive disease * HHT: hereditary hemorrhagic teleangiectasia * CIRCAD: cirrhosis cardiaque * Age \>18 years and \<100 years * Written informed consent obtained Exclusion Criteria: - withdrawal of written informed consent
Where this trial is running
Vienna
- Medical University of Vienna — Vienna, Austria (RECRUITING)
Study contacts
- Study coordinator: Thomas Reiberger, MD
- Email: thomas.reiberger@meduniwien.ac.at
- Phone: 0043140400
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Vascular Liver Disease, Portal Vein Thrombosis, Budd-Chiari Syndrome, Non-Cirrhotic Portal Hypertension, Rendu Osler Weber, Cardiac Cirrhosis, Porto-sinusoidal Vascular Disorder