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Clinical trial No longer in our active list Observational Ages 18 and up

Observational study on the use of Impella with VA ECMO

Official title: Abiomed Impella V-A ECMO AUTO Mode - Observational Study

Run by Abiomed Inc. · NCT05759377 · Data updated 2026-05-14

This study is no longer in our active list. It may have stopped recruiting or finished. The details below are as of 2026-05-14 and are kept for reference. Check ClinicalTrials.gov for its current status, or see similar studies below.

This study is trying to see how well the automated Impella device works with VA ECMO therapy in patients and how easy it is for doctors to use.

Quick facts

Study typeObservational
Ages18 Years and up
SexAll
Enrollment30 (estimated)
SponsorAbiomed Inc.
Industry-sponsored
Locations6 sites (Aachen, NRW and 5 other locations)
Trial IDNCT05759377 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are patients currently undergoing or scheduled for ECpella therapy.

Probably not a fit

Patients under 18 years old or those receiving treatment with a different ECMO setup or only the Impella CP® heart pump may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to collect data on the routine use of the Impella V-A ECMO AUTO Mode in patients undergoing ECpella therapy. It focuses on analyzing clinical effects, usability, and ease of use of the automated Impella mode in conjunction with a VA ECMO system. The study will gather clinical events to create a database for post-hoc analysis of the V-A ECMO AUTO Mode algorithm, while also assessing user experience through questionnaires and operational data. The goal is to enhance the understanding and development of the underlying algorithms in various clinical settings.

Why it matters

Potential benefit: If successful, this study could improve the management of heart failure patients receiving ECMO therapy by optimizing the use of the Impella device.

How similar studies have gone: While this approach is observational and builds on existing technologies, similar studies have shown promise in optimizing ECMO and Impella usage, indicating potential for success.

Who can join: the full rules

Show full inclusion / exclusion criteria 
Inclusion Criteria:

* Patients with ongoing or planned ECpella therapy

Exclusion Criteria:

* Age \< 18 years
* Treatment with other than VA ECMO setup
* Treatment with Impella CP® heart pump only

Where it's running

  • Uniklinik RWTH Aachen
    Aachen, Nrw, Germany     Recruiting
  • Hdz Nrw
    Bad Oeynhausen, Nrw, Germany     Recruiting
  • Herzzentrum Dresden GmbH
    Dresden, Saxony, Germany     Recruiting
  • Universitäres Herz- und Gefäßzentrum Hamburg
    Hamburg, Germany     Recruiting
  • UKGM Universtitätsklinikum Marburg
    Marburg, Germany     Not yet recruiting
  • Brüderkrankenhaus Trier
    Trier, Germany     Not yet recruiting

Study contacts

  • Principal investigator: Alexander Kersten, MD — Uniklinik RWTH Aachen
  • Study coordinator: Andreas Goetzenich, MD, PhD, MBA, FAHA, FESC
  • Email: agoetzenich@abiomed.com
  • Phone: +49 241 8860

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
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Heart Failure 1020Abiomed Inc. 4
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.