Observational study on α-synucleinopathy

A Registered Observational Cohort Study on α-Synucleinopathy

Fujian Medical University Union Hospital · NCT05527067

This study is trying to learn more about diseases like Parkinson's and dementia by collecting information over time to help doctors understand how these conditions change and progress.

Quick facts

Study typeObservational
Enrollment500 (estimated)
Ages30 Years to 80 Years
SexAll
SponsorFujian Medical University Union Hospital (other)
Locations1 site (Fuzhou, Fujian)
Trial IDNCT05527067 on ClinicalTrials.gov

What this trial studies

This observational study focuses on α-synucleinopathy, a group of neurodegenerative diseases that includes Parkinson's disease, multiple system atrophy, and dementia with Lewy bodies. It aims to collect data to enhance understanding of the natural history and progression of these conditions, utilizing multi-omics datasets. Data will be gathered both retrospectively at the time of research entry and prospectively during follow-up visits to aid healthcare providers in making informed medical decisions.

Who should consider this trial

Good fit: Ideal candidates include individuals with a clinical diagnosis of primary α-synucleinopathy and unrelated healthy controls.

Not a fit: Patients with secondary α-synucleinopathy or other neurological disorders, as well as pregnant or lactating women, may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could provide valuable insights that improve diagnosis and treatment strategies for patients with α-synucleinopathy.

How similar studies have performed: While this study is observational, similar studies have shown promise in understanding neurodegenerative diseases, suggesting potential for valuable findings.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Participants with a clinical diagnosis of primary α-synucleinopathy
* Unrelated healthy controls

Exclusion Criteria:

* Patients with secondary α-synucleinopathy that cannot be excluded.
* Patients with other neurological disorders.
* Pregnant or lactating women.

Where this trial is running

Fuzhou, Fujian

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: α-synucleinopathy

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.