Observational study on patients with ventricular tachycardia and cardiomyopathy

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

The END-VT study is a multicenter, prospective, longitudinal cohort study focusing on patients with cardiomyopathy-related ventricular tachycardia (VT). It aims to follow these patients from their first VT event for at least three years to determine the best treatment strategies for maximizing event-free survival. The study will also evaluate the epidemiology of VT, adherence to treatment guidelines, and the safety and effectiveness of current treatment options. Data will be collected through ICD remote monitoring and analyzed by clinical investigators to ensure unbiased results.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. Documented sustained ventricular arrhythmia (\>30 seconds as documented by an ECG, cardiac monitor, AED, and/or intracardiac pacemaker/ICD electrograms (EGMs);
2. First (new) diagnosis of VT;
3. Presence of or plan for ICD implant during index hospitalization;
4. Diagnosis of cardiomyopathy (ie. ICM, hypertrophic, dilated, restrictive, arrhythmogenic cardiomyopathy, or other scar),
5. ICD clinic follow-up planned, and
6. Age \>18 years old

Exclusion Criteria:

1\) Patients with VT due to a reversible cause

Where it's running

• Providence Health Care Society
  Vancouver, British Columbia, Canada Recruiting
• QEII Health Science Centre
  Halifax, Nova Scotia, Canada Recruiting
• Montreal Heart Institute,
  Montreal, Quebec, Canada Recruiting

Study contacts

• Principal investigator: Michelle Samuel, MPH, PhD — Montreal Heart Institute
• Study coordinator: John L Sapp, MD, FRCPC
• Email: john.sapp@nshealth.ca
• Phone: 902-473-4272

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Other studies for the same condition or treatment. Recruiting studies are listed first.

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.