Observational study on managing large colorectal polyps
The St. Paul's Hospital Advanced Endoscopic Resection Centre Cohort for Colorectal Neoplasia (SPARC-C): A Prospective Observational Study
This study is trying to see how well different endoscopic methods work for treating large colorectal polyps in patients over the next 10 years.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 3500 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | University of British Columbia Academic / other |
| Locations | 3 sites (Vancouver, British Columbia and 2 other locations) |
| Trial ID | NCT05402696 on ClinicalTrials.gov |
What this trial studies
The SPARC-C study is a prospective observational study focusing on patients referred for the management of large non-pedunculated colorectal polyps (LNPCPs). It aims to collect comprehensive data on patient demographics, lesion characteristics, procedural details, and clinical outcomes related to endoscopic resection techniques. The study will evaluate the effectiveness and safety of various endoscopic methods, including endoscopic mucosal resection and endoscopic submucosal dissection, over a period of 10 years with a target enrollment of 3500 participants. This research will help refine management strategies and improve patient outcomes in colorectal neoplasia.
Who should consider this trial
Good fit: Ideal candidates for this study are adults aged 18 and older who have been referred for the management of large non-pedunculated colorectal polyps.
Not a fit: Patients who are unable to provide informed consent or are pregnant or lactating will not benefit from this study.
Why it matters
Potential benefit: If successful, this study could enhance the management and treatment outcomes for patients with large colorectal polyps, potentially reducing the need for surgical interventions.
How similar studies have performed: Other studies have shown success with similar endoscopic approaches for managing colorectal polyps, indicating that this methodology is both established and promising.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients ≥ 18 years of age referred for the management of an LNPCP * Able to provide informed consent. Exclusion Criteria: * Unable to provide informed consent * Pregnant or lactating women.
Where this trial is running
Vancouver, British Columbia and 2 other locations
- Mount Saint Joseph Hospital — Vancouver, British Columbia, Canada (Active_not_recruiting)
- St. Paul's Hospital — Vancouver, British Columbia, Canada (Active_not_recruiting)
- Pacific Gastroenterology Associates — Vancouver, British Columbia, Canada (Recruiting)
Study contacts
- Study coordinator: Shirley X Jiang, MD
- Email: sjiangx@alumni.ubc.ca
- Phone: (604) 688-6332
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.