Observational study on managing large colorectal polyps
Official title: The St. Paul's Hospital Advanced Endoscopic Resection Centre Cohort for Colorectal Neoplasia (SPARC-C): A Prospective Observational Study
Run by University of British Columbia · NCT05402696 · Data updated 2026-11-12
This study is trying to see how well different endoscopic methods work for treating large colorectal polyps in patients over the next 10 years.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 3500 (estimated) |
| Sponsor | University of British Columbia Academic / other |
| Locations | 6 sites (Saint Cloud, Minnesota and 5 other locations) |
| Status | Recruiting |
| Started | June 27, 2022 |
| Main results expected | December 31, 2032 |
| Study ends | December 31, 2032 |
| Registry record updated | May 15, 2026 |
| Trial ID | NCT05402696 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are adults aged 18 and older who have been referred for the management of large non-pedunculated colorectal polyps.
✕Probably not a fit
Patients who are unable to provide informed consent or are pregnant or lactating will not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
The SPARC-C study is a prospective observational study focusing on patients referred for the management of large non-pedunculated colorectal polyps (LNPCPs). It aims to collect comprehensive data on patient demographics, lesion characteristics, procedural details, and clinical outcomes related to endoscopic resection techniques. The study will evaluate the effectiveness and safety of various endoscopic methods, including endoscopic mucosal resection and endoscopic submucosal dissection, over a period of 10 years with a target enrollment of 3500 participants. This research will help refine management strategies and improve patient outcomes in colorectal neoplasia.
Why it matters
Potential benefit: If successful, this study could enhance the management and treatment outcomes for patients with large colorectal polyps, potentially reducing the need for surgical interventions.
How similar studies have gone: Other studies have shown success with similar endoscopic approaches for managing colorectal polyps, indicating that this methodology is both established and promising.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients ≥ 18 years of age referred for the management of an LNPCP * Able to provide informed consent. Exclusion Criteria: * Unable to provide informed consent * Pregnant or lactating women.
Where it's running
-
St. Cloud Hospital
Saint Cloud, Minnesota, United States Recruiting -
Vancouver General Hospital
Vancouver, British Columbia, Canada Recruiting -
St. Paul's Hospital
Vancouver, British Columbia, Canada Recruiting -
Pacific Gastroenterology Associates
Vancouver, British Columbia, Canada Recruiting -
Mount Saint Joseph Hospital
Vancouver, British Columbia, Canada Active not recruiting -
Hadassah Ein Kerem Hospital
Jerusalem, Israel Active not recruiting
Study contacts
- Study coordinator: Shirley X Jiang, MD
- Email: sjiangx@alumni.ubc.ca
- Phone: (604) 688-6332
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.