Observational study on Epithelioid Sarcoma
Official title: Epithelioid Sarcoma. An Observational Study
Run by Italian Sarcoma Group · NCT03099681 · Data updated 2026-11-12
This study looks at people with Epithelioid Sarcoma to better understand the disease and its two types, hoping to improve treatment and outcomes for patients.
Quick facts
| Study type | Observational |
|---|---|
| Sex | All |
| Enrollment | 100 (estimated) |
| Sponsor | Italian Sarcoma Group Research network |
| Locations | 11 sites (Meldola, FC and 10 other locations) |
| Status | Recruiting |
| Started | August 22, 2017 |
| Main results expected | November 1, 2028 |
| Study ends | March 31, 2030 |
| Registry record updated | November 18, 2025 |
| Trial ID | NCT03099681 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates include individuals with a histological diagnosis of Epithelioid Sarcoma who can provide informed consent and comply with treatment or follow-up.
✕Probably not a fit
Patients with other malignancies within the past five years, except for certain skin cancers, may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This prospective national study in Italy aims to describe the population affected by Epithelioid Sarcoma (ES) and provide insights into the natural history of the disease. It will address outstanding questions regarding the management of ES and focus on the differences between its two variants: classical-type and proximal-type. The goal is to enhance understanding of the disease, tailor treatment approaches, and ultimately improve patient outcomes.
Why it matters
Potential benefit: If successful, this study could lead to more personalized treatment strategies for patients with Epithelioid Sarcoma.
How similar studies have gone: While this study focuses on a specific population and disease variant, similar observational studies have provided valuable insights into rare cancers, suggesting potential for success.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion criteria 1. Histological diagnosis of epithelioid sarcoma according to 2014 World Health Organization (WHO) classification, performed on biopsy or surgical specimen 2. Signed informed consent 3. Adequate patient compliance to treatment or follow up 4. No age limit Exclusion criteria 1. Other malignancies within past 5 years, with exception of carcinoma in situ of the cervix and basocellular skin cancers treated with eradicating intent 2. Impossibility to ensure adequate compliance
Where it's running
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Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori - IRST
Meldola, Fc, Italy Recruiting -
Istituto Europeo di Oncologia
Milan, Mi, Italy Recruiting -
Istituto Clinico Humanitas
Rozzano, Mi, Italy Recruiting -
Azienda Ospedaliera Universitaria Paolo Giaccone
Palermo, PA, Italy Recruiting -
Fondazione del Piemonte per l'Oncologia IRCC Candiolo
Candiolo, Torino, Italy Recruiting -
Istituto Ortopedico Rizzoli - Unit of Chemotherapy of Muscoloskeletal Tumors
Bologna, Italy Recruiting
Show 5 more locations
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Fondazione IRCCS INT Milano
Milan, Italy Recruiting -
Irccs Istituto Oncologico Veneto (Iov)
Padova, Italy Recruiting -
Ospedale Misericordia e Dolce Ist. Toscano Tumori, Az. USL4
Prato, Italy Recruiting -
Campus Biomedico
Roma, Italy Recruiting -
Istituti Fisioterapici Ospitalieri di Roma
Roma, Italy Recruiting
Study contacts
- Principal investigator: Paolo Casali, MD — Fondazione IRCCS INT Milano
- Study coordinator: Annamaria Frezza, MD
- Email: annamaria.frezza@istitutotumori.mi.it
- Phone: 003902390
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.