Clinical trial Recruiting at 11 sites Observational

Observational study on Epithelioid Sarcoma

Official title: Epithelioid Sarcoma. An Observational Study

Run by Italian Sarcoma Group · NCT03099681 · Data updated 2026-11-12

This study looks at people with Epithelioid Sarcoma to better understand the disease and its two types, hoping to improve treatment and outcomes for patients.

Quick facts

Study typeObservational
SexAll
Enrollment100 (estimated)
SponsorItalian Sarcoma Group
Research network
Locations11 sites (Meldola, FC and 10 other locations)
StatusRecruiting
StartedAugust 22, 2017
Main results expectedNovember 1, 2028
Study endsMarch 31, 2030
Registry record updatedNovember 18, 2025
Trial IDNCT03099681 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates include individuals with a histological diagnosis of Epithelioid Sarcoma who can provide informed consent and comply with treatment or follow-up.

Probably not a fit

Patients with other malignancies within the past five years, except for certain skin cancers, may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This prospective national study in Italy aims to describe the population affected by Epithelioid Sarcoma (ES) and provide insights into the natural history of the disease. It will address outstanding questions regarding the management of ES and focus on the differences between its two variants: classical-type and proximal-type. The goal is to enhance understanding of the disease, tailor treatment approaches, and ultimately improve patient outcomes.

Why it matters

Potential benefit: If successful, this study could lead to more personalized treatment strategies for patients with Epithelioid Sarcoma.

How similar studies have gone: While this study focuses on a specific population and disease variant, similar observational studies have provided valuable insights into rare cancers, suggesting potential for success.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion criteria

1. Histological diagnosis of epithelioid sarcoma according to 2014 World Health Organization (WHO) classification, performed on biopsy or surgical specimen
2. Signed informed consent
3. Adequate patient compliance to treatment or follow up
4. No age limit

Exclusion criteria

1. Other malignancies within past 5 years, with exception of carcinoma in situ of the cervix and basocellular skin cancers treated with eradicating intent
2. Impossibility to ensure adequate compliance

Where it's running

  • Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori - IRST
    Meldola, Fc, Italy
    Recruiting
  • Istituto Europeo di Oncologia
    Milan, Mi, Italy
    Recruiting
  • Istituto Clinico Humanitas
    Rozzano, Mi, Italy
    Recruiting
  • Azienda Ospedaliera Universitaria Paolo Giaccone
    Palermo, PA, Italy
    Recruiting
  • Fondazione del Piemonte per l'Oncologia IRCC Candiolo
    Candiolo, Torino, Italy
    Recruiting
  • Istituto Ortopedico Rizzoli - Unit of Chemotherapy of Muscoloskeletal Tumors
    Bologna, Italy
    Recruiting
Show 5 more locations
  • Fondazione IRCCS INT Milano
    Milan, Italy
    Recruiting
  • Irccs Istituto Oncologico Veneto (Iov)
    Padova, Italy
    Recruiting
  • Ospedale Misericordia e Dolce Ist. Toscano Tumori, Az. USL4
    Prato, Italy
    Recruiting
  • Campus Biomedico
    Roma, Italy
    Recruiting
  • Istituti Fisioterapici Ospitalieri di Roma
    Roma, Italy
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.