Observational study on Bicuspid Aortic Valve Disease

Prospective Cohort Study on Imaging Genetics of Bicuspid Aortic Valve

Observational Suzhou Municipal Hospital · NCT05656820

This study is tracking 200 patients with Bicuspid Aortic Valve disease over two years to see how their condition affects their heart health and to build a helpful database for future care.

Quick facts

Study typeObservational
Enrollment200 (estimated)
SexAll
SponsorSuzhou Municipal Hospital Academic / other
Locations1 site (Suzhou)
Trial IDNCT05656820 on ClinicalTrials.gov

What this trial studies

This observational study focuses on patients with Bicuspid Aortic Valve (BAV) disease, collecting clinical and ultrasound imaging data from over 30 hospitals in China. It aims to follow 200 outpatients and inpatients for two years to analyze prognostic characteristics and establish a comprehensive database for BAV patients. The study will evaluate various outcomes, including all-cause mortality and heart-related complications, using ultrasound imaging to assess different forms of valvular lesions.

Who should consider this trial

Good fit: Ideal candidates include patients diagnosed with Bicuspid Aortic Valve through ultrasound or other imaging tests.

Not a fit: Patients with Trileaflet Aortic Valve or significant aortic valve calcification will not benefit from this study.

Why it matters

Potential benefit: If successful, this study could enhance understanding of BAV disease and improve patient management strategies.

How similar studies have performed: While there have been studies on BAV, this specific approach of creating a comprehensive database through multi-center collaboration is relatively novel.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Ultrasound or other imaging tests to diagnose patients with BAV

Exclusion Criteria:

* Patients with TAV or/and have significant aortic valve calcification
* Those deemed unsuitable for enrollment by clinicians (e.g., end-stage patients, mentally ill patients, non-cooperating patients, etc.)
* Those who do not agree to be included

Where this trial is running

Suzhou

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Bicuspid Aortic Valve Disease
Last reviewed 2026-06-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.