Observational study of severe acute respiratory infections

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to gather data on patients with severe acute respiratory infections (SARI) admitted to hospitals and intensive care units during the winter months in both hemispheres. It will involve a 5 to 7-day cohort study across 20 to 40 participating sites globally, collecting clinical information and sample data as part of routine clinical practice. The primary goal is to establish a research response capability for future epidemics or pandemics, while the secondary aim focuses on understanding the epidemiology and microbiology of SARI.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* A history of feverishness or measured fever of ≥ 38 deg C;
* Cough;
* Dyspnoea (shortness of breath) OR Tachypnoea.

Exclusion Criteria:

• No exclusion criteria

Where it's running

• Australian and New Zealand Intensive Care Research Centre
  Melbourne, Victoria, Australia Recruiting

Study contacts

• Study coordinator: Nicole Ng, MBBS
• Email: mnhs-sprint.sari@monash.edu

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Effects of neuromuscular blocking agents and prone positioning on ARDS

  This study tests if using certain medications and positioning patients on their stomachs can help people with severe breathing problems from ARDS survive better while on a ventilator.

  Recruiting Assistance Publique Hopitaux De Marseille · Marseille · NCT06212492

• Clinical Multimodal Surveillance of Respiratory Pathogens

  This nationwide study tests a hospital-based system to track respiratory pathogens in patients with respiratory symptoms and to use samples collected during care to spot trends and support prevention efforts.

  Recruiting at 31 sites Huashan Hospital · Beijing, Beijing Municipality and 30 other locations · NCT07694648

• CRP point-of-care testing to guide antibiotic use for adults with respiratory symptoms in eight Jakarta primary care centers

  This trial tests whether using a C-reactive protein point-of-care test can help doctors in Jakarta decide when antibiotics are needed for adults with acute respiratory infections.

  Recruiting at 7 sites Oxford University Clinical Research Unit Indonesia · Jakarta and 7 other locations · NCT07717372

• Observational study on acute respiratory infections in primary care across Europe

  This study looks at how acute respiratory infections are treated in adults and children visiting primary care in Europe to help improve care and support future research.

  Recruiting at 3 sites European Clinical Research Alliance for Infectious Diseases (ECRAID) · Antwerp and 2 other locations · NCT06282718

• Observational study of acute respiratory infections in adults

  This study looks at how adults with acute respiratory infections are treated in hospitals across Europe to see what works best and improve patient care.

  Recruiting at 11 sites European Clinical Research Alliance for Infectious Diseases (ECRAID) · Antwerp and 26 other locations · NCT05814237

• National guideline program to reduce unnecessary antibiotics for colds and flu-like illnesses in Swiss primary care

  This project will test whether training family doctors to use new Swiss guidelines, point-of-care CRP testing, and shared decision-making can reduce unnecessary antibiotic prescriptions for adults with acute respiratory or flu-like illnesses in primary care.

  Recruiting Center for Primary Care and Public Health (Unisante), University of Lausanne, Switzerland · Lausanne, Canton of Vaud · NCT07396428

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.