Observational study of severe acute respiratory infections

Short Period Incidence Study of Severe Acute Respiratory Illness

Observational Australian and New Zealand Intensive Care Research Centre · NCT02498587

This study is trying to learn more about severe respiratory infections in hospitalized patients during winter to help prepare for future outbreaks.

Quick facts

Study typeObservational
Enrollment15000 (estimated)
SexAll
SponsorAustralian and New Zealand Intensive Care Research Centre Academic / other
Locations1 site (Melbourne, Victoria)
Trial IDNCT02498587 on ClinicalTrials.gov

What this trial studies

This observational study aims to gather data on patients with severe acute respiratory infections (SARI) admitted to hospitals and intensive care units during the winter months in both hemispheres. It will involve a 5 to 7-day cohort study across 20 to 40 participating sites globally, collecting clinical information and sample data as part of routine clinical practice. The primary goal is to establish a research response capability for future epidemics or pandemics, while the secondary aim focuses on understanding the epidemiology and microbiology of SARI.

Who should consider this trial

Good fit: Ideal candidates include patients with recent onset fever, cough, and either shortness of breath or rapid breathing requiring hospitalization.

Not a fit: Patients without symptoms of severe acute respiratory infection or those not requiring hospitalization may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could enhance preparedness and response strategies for future respiratory infection outbreaks.

How similar studies have performed: Previous observational studies on SARI have been crucial for understanding outbreaks, indicating that this approach has been effective in the past.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* A history of feverishness or measured fever of ≥ 38 deg C;
* Cough;
* Dyspnoea (shortness of breath) OR Tachypnoea.

Exclusion Criteria:

• No exclusion criteria

Where this trial is running

Melbourne, Victoria

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Severe Acute Respiratory Infection
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.