Observational study of hospitalized COVID-19 patients across multiple clinics
Hospitalised COVID-19 Patients Cohort Study in the EuCARE Project
Euresist Network GEIE · NCT05463380
This study looks at hospitalized COVID-19 patients from different clinics around the world to see how different virus strains and vaccines affect their illness and recovery.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 22000 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Euresist Network GEIE (other) |
| Locations | 10 sites (Düsseldorf and 9 other locations) |
| Trial ID | NCT05463380 on ClinicalTrials.gov |
What this trial studies
This observational multicentre study collects both retrospective and prospective data from hospitalized COVID-19 patients at 12 clinics across 11 countries and 4 continents. It aims to analyze the clinical course of COVID-19 in relation to various viral variants and the vaccines administered. The study will also gather biological materials for further analysis of immune responses and disease severity. By employing biostatistical methods and artificial intelligence, the research seeks to provide insights into optimizing clinical management based on viral characteristics and vaccination schedules.
Who should consider this trial
Good fit: Ideal candidates include hospitalized adults over 18 years old who have tested positive for SARS-CoV-2.
Not a fit: Patients who are not hospitalized or do not have a confirmed SARS-CoV-2 infection will not benefit from this study.
Why it matters
Potential benefit: If successful, this study could enhance understanding of COVID-19 treatment and management, leading to improved patient outcomes.
How similar studies have performed: Other studies have shown success in analyzing COVID-19 variants and their impact on patient outcomes, making this approach both relevant and necessary.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Hospitalized adult (\>18 years) patients including patients in the emergency ward * Positive for SARS-CoV-2 by PCR any time from 14 days before admission date until hospital discharge. Both first and recurrent episodes of COVID-19 will be included. * Having a signed informed consent when required by ethical approval Exclusion Criteria: none
Where this trial is running
Düsseldorf and 9 other locations
- Heinrich-Heine-Universität Düsseldorf — Düsseldorf, Germany (RECRUITING)
- ASST Santi Paolo e Carlo — Milan, Lombardy, Italy (RECRUITING)
- University of Rome Tor Vergata — Rome, Italy (RECRUITING)
- Kenya Medical Research Institute (KEMRI) — Nairobi, Kenya (RECRUITING)
- Vilnius universiteto ligoninė Santaros klinikos — Vilnius, Lithuania (RECRUITING)
- Regional Hospital Dr. Juan Graham Casasús, Villahermosa — Villahermosa, Mexico (RECRUITING)
- Centro Hospitalar Lisboa Ocidental — Lisbon, Portugal (RECRUITING)
- Karolinska Institutet — Stockholm, Sweden (RECRUITING)
- Poole University Hospitals, Dorset — Poole, United Kingdom (RECRUITING)
- Bach Mai Hospital — Hanoi, Vietnam (RECRUITING)
Study contacts
- Study coordinator: FRANCESCA INCARDONA Project Coordinator
- Email: francesca.incardona@euresist.org
- Phone: +393356112830
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: COVID-19