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Observational study of acute respiratory infections in adults

Perpetual Observational Study of Acute Respiratory Infections Presenting Via Emergency Rooms and Other Acute Hospital Care Settings

Observational European Clinical Research Alliance for Infectious Diseases (ECRAID) · NCT05814237

This study looks at how adults with acute respiratory infections are treated in hospitals across Europe to see what works best and improve patient care.

Quick facts

Study typeObservational
Enrollment11750 (estimated)
Ages18 Years and up
SexAll
SponsorEuropean Clinical Research Alliance for Infectious Diseases (ECRAID) Academic / other
Locations23 sites (Brussels and 22 other locations)
Trial IDNCT05814237 on ClinicalTrials.gov

What this trial studies

The POS-ARI-ER study is an observational study aimed at characterizing acute respiratory infections (ARIs) in adults presenting to hospitals across Europe. It focuses on the diagnostic and therapeutic practices used in the management of ARIs, as well as the clinical outcomes of patients. The study will collect data on routine diagnostic methods and pharmacological interventions through standardized report forms, providing insights into the etiology of ARIs and the effectiveness of current treatment strategies. By evaluating the implementation of advanced diagnostic technologies, the study seeks to improve patient outcomes and reduce antimicrobial resistance.

Who should consider this trial

Good fit: Ideal candidates for this study are adults aged 18 years and older who present to emergency rooms with a clinical suspicion of a new episode of acute respiratory tract infection.

Not a fit: Patients who have been transferred from another hospital or those who have been admitted for more than two days at the time of enrollment may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to improved diagnostic and treatment strategies for acute respiratory infections, enhancing patient care and outcomes.

How similar studies have performed: Other studies have shown success in utilizing advanced diagnostic methods for respiratory infections, indicating that this approach has potential for meaningful impact.

Eligibility criteria

Show full inclusion / exclusion criteria 
Inclusion Criteria:

* Age ≥ 18 years
* Clinical suspicion of a new episode of acute respiratory tract infection, with onset in the last 10 days
* Patient presents to an emergency room or secondary care setting
* Informed consent is provided by patient or their legal representative

Exclusion Criteria:

* Patient has been transferred from another hospital
* Patient admitted to hospital for \>2 days at the time of enrolment
* Patient has been previously enrolled in the POS-ARI-ER study

Where this trial is running

Brussels and 22 other locations

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
View on ClinicalTrials.gov → Find more trials like this →
Conditions Acute Respiratory InfectionAcute Respiratory Tract InfectionInfectionsCommunicable Diseases
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.