Observational look at how adults with stomach and GEJ cancer are diagnosed and treated in Greece
Official title: Epidemiological Characteristics And Management Strategies Of Gastric/Gastrophaegal Junction Cancer Patients In Routine Clinical Practice: A Greek Multicenter Observational Study (The GRACE Study)
Run by AstraZeneca · NCT07800754 · Data updated 2026-11-12
This study will look at real-world care for adults with stage II-IVB gastric or gastroesophageal junction cancer in Greece to see how they are diagnosed and managed in usual practice.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years to 130 Years |
| Sex | All |
| Enrollment | 300 (estimated) |
| Sponsor | AstraZeneca Industry-sponsored |
| Locations | 9 sites (Alexandroupoli and 8 other locations) |
| Status | Recruiting |
| Started | September 30, 2026 |
| Main results expected | December 31, 2027 |
| Study ends | December 31, 2027 |
| Registry record updated | November 9, 2026 |
| Trial ID | NCT07800754 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults 18 years or older with histologically confirmed stage II to IVB gastric or GEJ adenocarcinoma diagnosed between June 1, 2025 and the end of the recruitment period (Q3 2027).
✕Probably not a fit
Patients who have concurrent primary cancers requiring systemic treatment or who participate in interventional trials may not directly benefit from this observational study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This multicenter, Greece-only observational study collects retrospective and prospective data to describe epidemiology and management patterns of stage II-IVB gastric/GEJ adenocarcinoma in routine clinical care. It is non-interventional and seeks to document outcomes as patients undergo standard treatment chosen by their clinicians. Participation is voluntary and can be withdrawn at any time, with efforts made to capture outcomes. The study is sponsored by AstraZeneca and involves several Greek research sites. Data collection spans from June 1, 2025 through the end of the recruitment period in Q3 2027.
Why it matters
Potential benefit: Findings could help understand real-world treatment patterns and outcomes to inform future care for gastric/GEJ cancer patients in Greece.
How similar studies have gone: Real-world observational studies in gastric cancer have provided valuable insights into treatment patterns and outcomes in other settings, supporting the relevance of this approach in Greece.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients aged ≥18 years upon gastric/GEJ adenocarcinoma diagnosis. * Written signed and dated informed consent by the patient (or their legally acceptable representative, as applicable). For deceased patients on the date of study entry a waiver of consent must be approved by the Hospital EC/IRB. * Patients diagnosed with histologically confirmed, stage II to IVB adenocarcinoma of gastric/GEJ, between June 1st, 2025 and the end of the recruitment period (Q3 2027). Exclusion Criteria: * Patients who participate or participated during the data collection period (prospective and retrospective) in any clinical investigation/clinical trial that includes interventions that fall outside the everyday clinical practice. * Patients who have participated in the design and/or the conduct of the study. * Patients with another primary malignancy within the last 5 years, for which systemic anticancer treatment is required after the diagnosis of gastric/GEJ cancer.
Where it's running
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Research Site
Athens, Greece Recruiting -
Research Site
Crete, Greece Recruiting -
Research Site
Thessaloniki, Greece Recruiting -
Research Site
Alexandroupoli, Greece Not yet recruiting -
Research Site
Athens, Greece Not yet recruiting -
Research Site
Athens, Greece Withdrawn
Show 3 more locations
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Research Site
Ioannina, Greece Not yet recruiting -
Research Site
Pátrai, Greece Not yet recruiting -
Research Site
Thessaloniki, Greece Not yet recruiting
Study contacts
- Study coordinator: AstraZeneca Clinical Study Information Center
- Email: information.center@astrazeneca.com
- Phone: 877-240-9479
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.