Clinical trial Recruiting at 1 site Observational Ages 18 and up

Observational cohort of liver cancer patients in France

Official title: Prospective Cohort of Patients With Hepatocellular Carcinoma in France

Run by Centre Hospitalier Universitaire, Amiens · NCT04348838 · Data updated 2026-11-12

This study is collecting information from liver cancer patients in France to better understand how the disease progresses and how different treatments work.

More Hepatocellular Carcinoma trials

Quick facts

Study typeObservational
Ages18 Years and up
SexAll
Enrollment5000 (estimated)
SponsorCentre Hospitalier Universitaire, Amiens
Academic / other
Locations1 site (Amiens)
StatusRecruiting
StartedSeptember 26, 2019
Main results expectedSeptember 30, 2027
Study endsDecember 31, 2027
Registry record updatedJune 10, 2025
Trial IDNCT04348838 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates include individuals with new or suspected cases of hepatocellular carcinoma, regardless of the cause or stage of the disease.

Probably not a fit

Patients with serious life-threatening conditions unrelated to liver disease or those in vulnerable populations may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study aims to collect and analyze data from patients diagnosed with hepatocellular carcinoma (HCC) in France. It focuses on understanding the disease's progression, treatment responses, and outcomes by gathering information from new and existing cases of HCC across multiple centers. The project seeks to address the challenges associated with HCC, including late diagnosis and the need for improved diagnostic and therapeutic strategies. By creating a comprehensive database, the study hopes to enhance knowledge and facilitate future research in this area.

Why it matters

Potential benefit: If successful, this study could lead to improved diagnosis and treatment options for patients with hepatocellular carcinoma.

How similar studies have gone: Other studies focusing on cohort data collection for liver cancer have shown promise in improving understanding and treatment, making this approach both relevant and potentially impactful.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* New cases of HCC
* suspected case of HCC regardless of the cause, stage, treatment
* Known HCC: drug treatment for recurrence or progression

Exclusion Criteria:

* Associated serious condition threatening life in the short term (with the exception of liver disease itself)
* So-called vulnerable populations: minors, persons under guardianship or temporary guardianship, or person deprived of their liberty by an administrative or judicial decision

Where it's running

  • CHU Amiens
    Amiens, France
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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  • BGB-B2033 vs Sorafenib or Lenvatinib for advanced liver cancer

    This study tests whether the investigational drug BGB-B2033 can help people with advanced hepatocellular carcinoma when given after prior PD-1/PD-L1 therapy, compared with the standard medicines sorafenib or lenvatinib.

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  • Zinc add-on with targeted therapy plus immunotherapy for advanced liver cancer

    This study tests whether adding daily zinc to standard targeted therapy and immunotherapy helps people with unresectable or advanced hepatocellular carcinoma.

    Recruiting Phase 2 Anhui Provincial Hospital · Hefei, Anhui · NCT07793695

  • 68Ga-SorB PET/CT imaging for solid tumors

    This study tests a new PET tracer called 68Ga-SorB to see if it can safely and accurately detect tumors in adults with melanoma, liver, lung, breast, pancreatic, ovarian cancer, or cholangiocarcinoma.

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  • Hepatocellular Carcinoma Patient Registry (CHARM Hepatocellular Carcinoma MEA)

    This observational study collects medical records of adults with hepatocellular carcinoma to understand how the disease presents and progresses across regions in the Middle East and North Africa.

    Recruiting AstraZeneca · Al Mansurah and 16 other locations · NCT07650773

  • GLP-1 RA plus standard treatment in first-line metastatic GI cancers

    This early-phase trial tests whether adding a GLP-1 receptor agonist to standard first-line chemotherapy is safe and feasible for people with metastatic pancreatic, colorectal, or liver cancer.

    Recruiting Early Phase 1 University of Arizona · Tucson, Arizona · NCT07627191

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.