Nutrition and metabolic profiling in people with lung cancer to create personalized diet plans

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study will gather clinical, nutritional, and metabolic information from adults with non-small cell and small cell lung cancer across multiple centers, alongside a cohort of healthy volunteers as controls. Participants aged 18–85 will include people receiving chemotherapy, immunotherapy, combination or biological therapies, conservative care, or no active treatment, with exclusions for uncontrolled chronic disease or acute gastrointestinal illness. Collected data will be used to characterize nutritional impairment patterns and metabolic changes associated with lung cancer and its treatments. The goal is to use these patterns to develop a precision nutrition model that can suggest individualized dietary strategies.

Why it matters

Who can join: the full rules

Inclusion Criteria

• Study population cohort: Patients of both sexes Patients aged between 18 and 85 years Patients diagnosed with lung cancer (non-small cell and small cell) Patients treated with chemotherapy, immunotherapy, combinations of immunotherapy and biological therapy, patients receiving conservative therapy, without active treatment, or any other type of treatment, according to ESMO and NCCN guidelines for the management of metastatic lung cancer (small cell and non-small cell)

• Control population cohort: Volunteers of both sexes Volunteers aged between 18 and 85 years Volunteers free of oncological disease

Exclusion Criteria

• Study population cohort: Patients with uncontrolled chronic diseases Patients with acute gastrointestinal diseases

• Control population cohort: Volunteers with uncontrolled chronic diseases Volunteers with acute gastrointestinal diseases Volunteers who have had any type of oncological condition at any point in their lives Volunteers with diagnosed pulmonary pathology: chronic lung disease, asthma, pulmonary fibrosis, bronchiectasis, interstitial lung disease, recent pneumonia (3-6 months), moderate/severe sleep apnea, latent or previous tuberculosis with sequelae Volunteers with underlying autoimmune diseases: rheumatoid arthritis, systemic lupus erythematosus, multiple sclerosis Volunteers with active or chronic infections: HIV, hepatitis B or C, recurrent chronic infections, tuberculosis

Where it's running

• University Hospital of Parma
  Parma, Parma, Italy Recruiting
• IMDEA Nutrition
  Madrid, Madrid, Spain Recruiting
• Infanta Sofía University Hospital
  San Sebastián de los Reyes, Madrid, Spain Recruiting

Study contacts

• Study coordinator: Juan Moreno Rubio
• Email: jmrubio@salud.madrid.org
• Phone: +34911914164

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.