Nurse-led self-management to help taste change during taxane chemotherapy
Official title: The Effect of a Nurse-Led Self-Management Program on Taste Alteration, Nutritional Status, and Quality of Life in Women With Breast Cancer Receiving Taxane-Based Chemotherapy: A Randomized Controlled Trial
Run by Izmir Bakircay University · NCT07670221 · Data updated 2026-11-12
This study tests whether a nurse-guided self-management program can help women with breast cancer handle taste changes during taxane chemotherapy.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | Women only |
| Enrollment | 68 (estimated) |
| Sponsor | Izmir Bakircay University Academic / other |
| Drugs / interventions | chemotherapy |
| Locations | 1 site (Izmir) |
| Status | Recruiting |
| Started | February 16, 2026 |
| Main results expected | July 19, 2026 |
| Study ends | August 24, 2026 |
| Registry record updated | June 26, 2026 |
| Trial ID | NCT07670221 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Women with breast cancer currently receiving taxane-based chemotherapy who have a CTCAE v4.0 taste alteration score of 1 or 2 after the first chemo cycle and can provide informed consent.
✕Probably not a fit
Participants without taste alteration or those not benefiting from self-management strategies may not experience notable improvements in taste or nutrition.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This is a parallel-group randomized controlled trial evaluating a nurse-led self-management program added to routine care versus routine care alone in women with breast cancer receiving taxane-based chemotherapy. The program helps participants recognize, monitor, and manage taste alterations and related nutritional issues during treatment. Outcomes focus on taste alteration, nutritional status, and quality of life, using CTCAE v4.0 criteria for baseline taste changes and standard follow-up assessments. Eligible participants are adults with breast cancer undergoing taxane chemotherapy, literate, and willing to consent. The study aims to determine if structured nursing support improves patient-reported and clinical endpoints related to taste changes and nutrition.
Why it matters
Potential benefit: If successful, participants may experience improved taste function, better nutritional status, and enhanced quality of life during chemotherapy.
How similar studies have gone: Prior work suggests behavioral and nursing-led interventions can support symptom management, but evidence specific to taxane-related taste changes is limited.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Aged 18 years or older * Literate * Diagnosed with breast cancer * Receiving taxane-based chemotherapy * Having a score of 1 or 2 for taste alteration according to the Common Terminology Criteria for Adverse Events version 4.0 (CTCAE v4.0) after the first cycle of chemotherapy * Willing to participate in the study and providing written informed consent Exclusion Criteria: * Having any communication barrier that prevents participation in the study * Having a diagnosed psychiatric disorder * Receiving radiotherapy * Having metastasis * Having a diagnosed physical disease that may affect food intake, such as ulcerative colitis or Crohn's disease * Receiving enteral or parenteral nutrition support
Where it's running
-
Izmir Provincal Health Directorate Izmir City Hospital
Izmir, Turkey (Türkiye) Recruiting
Study contacts
- Study coordinator: Pinar Zorba Bahceli, PhD
- Email: pinarzorba85@gmail.com
- Phone: +90 553 487 25 50
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.