Nurse-led preemptive symptom management for head and neck cancer patients during radiation therapy

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

Adults with confirmed non-metastatic head and neck cancer who are scheduled for postoperative adjuvant or radical radiotherapy (with or without concurrent chemotherapy) will be enrolled at West China Hospital. Participants will receive either a nurse-led preemptive symptom management protocol delivered throughout the radiotherapy course or conventional care, with procedures and contacts occurring in person at the treatment center. The primary outcome is the rate of radiation therapy interruptions; secondary outcomes include symptom severity, quality of life, and psychological well-being measured by validated questionnaires. Data will be compared between the two groups to determine whether the preemptive nursing protocol reduces interruptions and improves patient-reported outcomes.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. Patients had pathologically confirmed malignant head and neck tumors without distant metastasis.
2. Patient age ≥18 years; Patients were scheduled to undergo either postoperative adjuvant radiotherapy or radical radiotherapy, with or without concurrent chemotherapy.
3. Baseline ECOG (Eastern Cooperative Oncology Group) score 0-2;
4. Good cognitive and reading skills, able to complete the questionnaire survey.

Exclusion Criteria:

1. Presence of other malignant tumors aside from head and neck malignancies;
2. A history of prior head and neck radiotherapy;
3. Mental illness or cognitive impairments;
4. Uncontrolled systemic diseases that could significantly affect their QoL.

Where it's running

• West China Hospital of Sichuan University
  Chengdu, Sichuan, China Recruiting

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.