Nurse-led cognitive training for patients with mild cognitive impairment

Effectiveness of Nurse-led Clinics Training Program on Mild Cognitive Impairment Patients: a Randomized Controlled Trial Protocol

NA · Xuanwu Hospital, Beijing · NCT06198530

This study is testing whether cognitive training led by nurses can help people with mild cognitive impairment improve their thinking skills and overall well-being compared to training done at home.

Quick facts

PhaseNA
Study typeInterventional
Enrollment96 (estimated)
Ages18 Years and up
SexAll
SponsorXuanwu Hospital, Beijing (other)
Locations1 site (Beijing)
Trial IDNCT06198530 on ClinicalTrials.gov

What this trial studies

This trial tests the effectiveness of a nurse-led clinics cognitive training program for patients with mild cognitive impairment (MCI) using a single-blind, randomized controlled design. Participants will be divided into two groups: one receiving cognitive training in nurse-led clinics and the other receiving home-based training. The study aims to assess various outcomes, including cognitive function, anxiety and depression levels, quality of life, and daily living abilities over a 12-month period. The primary measure of cognitive function will be the Mini-Mental State Examination, with additional neuropsychological assessments and EEG results analyzed for further insights.

Who should consider this trial

Good fit: Ideal candidates are literate Han Chinese individuals over 18 years old with a diagnosis of mild cognitive impairment.

Not a fit: Patients with severe aphasia, significant physical disabilities, or other serious health conditions may not benefit from this study.

Why it matters

Potential benefit: If successful, this program could help slow cognitive decline and improve the quality of life for patients with mild cognitive impairment.

How similar studies have performed: While this approach is innovative, similar studies have shown promise in cognitive training interventions for cognitive impairments.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Subjects with informed consent;
* Literate Han Chinese, above the age of 18;
* At least 6 years of education;
* Neither normal nor demented according to the criteria of the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, with a Clinical Dementia Rating(CDR) ≥0.5 on at least one domain and a global score ≤0.5; a Mini-Menta State Examination score ≥20 (primary school), or ≥24 (junior school or above).
* having normal vision and hearing with/without corrective devices.

Exclusion Criteria:

* Severe aphasia, physical disabilities, or any other factor that might preclude completion of neuropsychological testing.
* Clinically significant gastrointestinal, renal, hepatic, respiratory, infectious, endocrine, or cardiovascular system disease; cancer; alcoholism; drug addiction.
* Illnesses affecting mobility or are unable to accept assessments or interventions that are required in this study.

Where this trial is running

Beijing

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Mild Cognitive Impairment, nurse-led clinics, computerized cognitive training, randomized controlled clinical trial

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.