NORAHOME: Home-based multimodal monitoring and care for people with minor stroke and TIA
NORA-HOME. Efficiency And Safety An Ambulatory Multimodal Monitoring Model In Patients With Minor Stroke And Transient Ischemic Attacks
This project tests whether giving adults with minor stroke or TIA a multimodal home-hospitalization program can be as safe, reduce complications, and be more efficient than standard hospital care.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 250 (estimated) |
| Sex | All |
| Sponsor | Hospital Universitari Vall d'Hebron Research Institute Academic / other |
| Locations | 1 site (Barcelona) |
| Trial ID | NCT07500116 on ClinicalTrials.gov |
What this trial studies
NORAHOME compares a multimodal home-hospitalization pathway to standard clinical practice for adults who present to the emergency department with minor stroke or TIA. Eligible patients who are clinically stable, have family or caregiver support and a smartphone receive coordinated remote monitoring, home nursing/clinical visits, and early initiation of secondary prevention instead of routine inpatient admission. The main goals are to lower early stroke recurrence and hospital readmissions while maintaining safety, and to measure patient-reported outcomes and efficiency. The program is delivered from Vall d'Hebron and participation is voluntary with informed consent.
Who should consider this trial
Good fit: Adults over 18 who present to the ED with TIA (full recovery <24 hours) or minor stroke (NIHSS ≤ 5), are clinically stable, have a smartphone and caregiver support, and can give informed consent.
Not a fit: Patients needing urgent reperfusion or revascularization for severe stenosis/occlusion, those with major pre-existing neurological or psychiatric conditions, terminal illness, or barriers to follow-up (for example language or lack of caregiver/smartphone) are unlikely to benefit from home hospitalization.
Why it matters
Potential benefit: If successful, patients could avoid routine hospital admission while receiving close monitoring and faster preventive care at home, potentially lowering complications and improving experience.
How similar studies have performed: Hospital-at-home and outpatient TIA clinic models have shown feasibility and some benefits in other settings, but multimodal home hospitalization specifically for TIA/minor stroke remains relatively limited and needs formal validation.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: Patients presenting to the Emergency Department with symptoms of TIA (complete recovery of neurological deficits within \<24 hours) or minor stroke (NIHSS ≤ 5) * Age \>18 years. * Availability of a smartphone for the patient or caregiver. * Family support and/or formal caregiver. * Clinical stability during the last 12 hours in the Emergency Department. * Signed informed consent by the patient and/or family member or legal representative. Exclusion Criteria: * Severe stenosis or symptomatic arterial occlusion requiring admission for potential reperfusion and/or arterial revascularization treatments. * Patients with pre-existing neurological or psychiatric conditions that may interfere with or complicate follow-up and evaluations. * Clinical (terminal condition) or social (language barrier) impossibility to complete follow-up assessments.
Where this trial is running
Barcelona
- Vall Hebron University Hospital — Barcelona, Spain (Recruiting)
Study contacts
- Study coordinator: Marian Muchada Lopez, MD, PHD
- Email: mangeles.muchada@vallhebron.cat
- Phone: +34 934893000
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.