Non-thrust lumbar and sacral mobilizations for mechanical low back pain
Official title: Non-Thrust Lumbar and Sacral Mobilizations in Mechanical Low Back Pain
Run by Foundation University Islamabad · NCT07334756 · Data updated 2026-11-12
This study will see if adding sacral mobilizations to lumbar mobilizations helps adults aged 18–45 with chronic mechanical low back pain reduce pain and improve movement and daily function.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years to 45 Years |
| Sex | All |
| Enrollment | 40 (estimated) |
| Sponsor | Foundation University Islamabad Academic / other |
| Locations | 1 site (Islamabad, Punjab Province) |
| Status | Recruiting |
| Started | January 15, 2025 |
| Main results expected | December 31, 2025 |
| Study ends | January 15, 2026 |
| Registry record updated | January 12, 2026 |
| Trial ID | NCT07334756 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults aged 18–45 with chronic (over 3 months) mechanical low back pain localized from T12 to the buttock line and without leg pain are the intended participants.
✕Probably not a fit
People with leg pain or neurological symptoms, structural spine deformities, recent spinal or abdominal surgery, pregnancy, inflammatory or degenerative spinal diseases, malignancy, or acute flares are unlikely to benefit from this protocol.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This randomized controlled trial compares two hands-on treatment approaches: lumbar mobilizations alone versus lumbar plus sacral mobilizations in adults with chronic mechanical low back pain without leg symptoms. Participants receive non-thrust manual therapy and are followed for changes in pain, lumbar range of motion, lumbar proprioception, and functional disability. Adults aged 18–45 with low back pain lasting more than three months are eligible, while those with radicular symptoms, structural spinal deformity, recent surgery, inflammatory or degenerative spinal disease, pregnancy, or malignancy are excluded. The trial is conducted at Foundation University Islamabad with participants required to attend in-person treatment sessions.
Why it matters
Potential benefit: If successful, adding sacral mobilizations could reduce pain and improve lumbar range of motion, proprioception, and daily function for people with mechanical low back pain.
How similar studies have gone: Manual lumbar mobilization has supportive evidence for some patients with low back pain, while specifically adding sacral mobilizations has been studied less and has only limited supportive data from small trials.
Who can join: the full rules
Show full inclusion / exclusion criteria
* Inclusion Criteria Adults 18 to 45 years Both genders Low back (from T12 to buttock line) pain for more than 3 months The CMLBP is the chief complaint without leg pain. * Exclusion Criteria Acute flare Low Back Pain Thoracic pain Trauma to the spine causing fracture and disruption of the ligaments Leg symptoms when walk, eased in flexion (Signs of stenosis) Paresthesia/numbness Structural deformity (scoliosis, spondylosis, spondylolisthesis) Curve reversal Pregnancy Post-surgery (within 6 months of abdominal or spinal/lower limb surgery) Degenerative and inflammatory spinal diseases Malignancy Centralization and peripheralization
Where it's running
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Foundation University Islamabad
Islamabad, Punjab Province, Pakistan Recruiting
Study contacts
- Study coordinator: Qurat ul ain Sara Ahmed, DPT
- Email: quratulainsaraahmed@gmail.com
- Phone: 03351182403
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.