Non-thrust lumbar and sacral mobilizations for mechanical low back pain

Non-Thrust Lumbar and Sacral Mobilizations in Mechanical Low Back Pain

Not applicable Interventional Foundation University Islamabad · NCT07334756

This study will see if adding sacral mobilizations to lumbar mobilizations helps adults aged 18–45 with chronic mechanical low back pain reduce pain and improve movement and daily function.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment40 (estimated)
Ages18 Years to 45 Years
SexAll
SponsorFoundation University Islamabad Academic / other
Locations1 site (Islamabad, Punjab Province)
Trial IDNCT07334756 on ClinicalTrials.gov

What this trial studies

This randomized controlled trial compares two hands-on treatment approaches: lumbar mobilizations alone versus lumbar plus sacral mobilizations in adults with chronic mechanical low back pain without leg symptoms. Participants receive non-thrust manual therapy and are followed for changes in pain, lumbar range of motion, lumbar proprioception, and functional disability. Adults aged 18–45 with low back pain lasting more than three months are eligible, while those with radicular symptoms, structural spinal deformity, recent surgery, inflammatory or degenerative spinal disease, pregnancy, or malignancy are excluded. The trial is conducted at Foundation University Islamabad with participants required to attend in-person treatment sessions.

Who should consider this trial

Good fit: Adults aged 18–45 with chronic (over 3 months) mechanical low back pain localized from T12 to the buttock line and without leg pain are the intended participants.

Not a fit: People with leg pain or neurological symptoms, structural spine deformities, recent spinal or abdominal surgery, pregnancy, inflammatory or degenerative spinal diseases, malignancy, or acute flares are unlikely to benefit from this protocol.

Why it matters

Potential benefit: If successful, adding sacral mobilizations could reduce pain and improve lumbar range of motion, proprioception, and daily function for people with mechanical low back pain.

How similar studies have performed: Manual lumbar mobilization has supportive evidence for some patients with low back pain, while specifically adding sacral mobilizations has been studied less and has only limited supportive data from small trials.

Eligibility criteria

Show full inclusion / exclusion criteria
* Inclusion Criteria Adults 18 to 45 years Both genders Low back (from T12 to buttock line) pain for more than 3 months The CMLBP is the chief complaint without leg pain.
* Exclusion Criteria Acute flare Low Back Pain Thoracic pain Trauma to the spine causing fracture and disruption of the ligaments Leg symptoms when walk, eased in flexion (Signs of stenosis) Paresthesia/numbness Structural deformity (scoliosis, spondylosis, spondylolisthesis) Curve reversal Pregnancy Post-surgery (within 6 months of abdominal or spinal/lower limb surgery) Degenerative and inflammatory spinal diseases Malignancy Centralization and peripheralization

Where this trial is running

Islamabad, Punjab Province

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Mechanical Low Back Pain
Last reviewed 2026-06-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.