Non-invasive spinal stimulation to improve walking in neurological patients

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study evaluates the effects of non-invasive spinal cord stimulation on walking function in individuals with neurological disorders, such as cerebral palsy and stroke. Participants will undergo a cross-over design where they will receive intensive gait training either alone or combined with spinal stimulation. The study aims to assess the impact of this stimulation on spasticity and locomotor function, as well as gather participant feedback on their experiences. The intervention will last up to 11 months, with participants attending up to five sessions per week.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* have a neurologic condition
* can walk 20 yards, with or without an assistive device
* have stable medical condition
* are capable of performing simple cued motor tasks and who can follow 2-3 step commands
* have ability to attend up to 5 sessions per week physical therapy sessions and testing activities
* have adequate social support to be able to participate in training and assessment sessions, up to 5 sessions per week, for the duration of up to 11 months within the study period.
* who are volunteering to be involved in this study
* can read and speak English

Exclusion Criteria:

* have significant medical disease; including uncontrolled systemic hypertension with values above 170/100 mmHg; cardiac or pulmonary disease; uncorrected coagulation abnormalities or need for therapeutic anticoagulation.
* have cardiovascular or musculoskeletal disease or injury that would prevent full participation in physical therapy intervention
* have a history of uncontrolled seizures
* have unhealed fracture or other musculoskeletal impairment that might interfere with lower extremity rehabilitation or testing activities
* are dependent on ventilation support
* have implanted stimulator (e.g. epidural stimulator, vagus nerve stimulator, pacemaker, cochlear implant, etc) or drug delivery device (e.g. baclofen pump)
* have history of orthopedic surgery in lower extremities or neurosurgery that may be a confounding factor for interpretation of the results (such as tendon transfer, tendon or muscle lengthening for spasticity management, injection therapies to lower extremity muscles, etc.) in last 12 months
* have established osteoporosis and taking medication for osteoporosis treatment.
* have rheumatic diseases (rheumatoid arthritis, systemic lupus erythematosus, etc.)
* have active cancer

Where it's running

• University of Washington
  Seattle, Washington, United States Recruiting

Study contacts

• Principal investigator: Katherine M Steele, PhD — University of Washington
• Study coordinator: Siddhi R Shrivastav, BPTh, MS
• Email: siddhis@uw.edu
• Phone: 973-444-1940

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Virtual intervention for at-risk children with neurological issues

  This study is testing if a virtual program can help young children with neurological issues, like those born prematurely, just as well as in-person help does.

  Recruiting University of Wisconsin, Madison · Madison, Wisconsin · NCT06643598

• Sensory Integration Therapy vs Conventional Physical Therapy in Children With Mixed Cerebral Palsy

  This study tests whether Sensory Integration Therapy helps improve gross motor function more than standard physical therapy in children aged 4–10 with mixed cerebral palsy.

  Recruiting Riphah International University · Peshawar, Kpk · NCT07921069

• Turkish version of ABILHAND-Kids Young CP: translation, adaptation, and reliability

  A Turkish version of the ABILHAND-Kids Young CP questionnaire is being created and tested to see if it reliably measures manual ability in 2-to-7-year-olds with cerebral palsy, based on parent reports.

  Recruiting Istanbul University - Cerrahpasa · Istanbul, Istanbul · NCT07894926

• Multisite upper limb surgery in children with unilateral cerebral palsy

  This study looks at whether individualized multisite upper limb surgery helps improve hand function in kids with hemiplegic cerebral palsy, using each child as their own control before and after surgery.

  Recruiting Centre Médico-Chirurgical de Réadaptation des Massues Croix Rouge Française · Lyon · NCT07891078

• Spinal Stimulation During Walking to See If Spasticity Lessens in Cerebral Palsy

  This study tests whether walking with non-invasive spinal stimulation reduces leg muscle tightness and improves walking in children and young adults with cerebral palsy.

  Recruiting University of Washington · Seattle, Washington · NCT07826494

• Combined leg nerve blocks for kids with cerebral palsy after surgery

  This study tests whether adding two nerve blocks to standard anesthesia helps control pain in children with cerebral palsy after lower limb surgery.

  Recruiting Diskapi Yildirim Beyazit Education and Research Hospital · Ankara · NCT07801365

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.