Non-invasive measurement of intracranial pressure using video technology
Non-Invasive and Non-Contact Intracranial Pressure Waveform Recording Using Dynamic Video Ophthalmoscopy
This study is testing a new video tool to measure pressure inside the skull without needing surgery or anesthesia, aiming to make it safer and more comfortable for patients with certain brain conditions.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 90 (estimated) |
| Ages | 4 Years and up |
| Sex | All |
| Sponsor | University of Minnesota Academic / other |
| Locations | 1 site (Minneapolis, Minnesota) |
| Trial ID | NCT04046523 on ClinicalTrials.gov |
What this trial studies
This study tests a video ophthalmoscope to measure intracranial pressure (ICP) without invasive techniques or anesthesia. It aims to provide a safer alternative for monitoring ICP in patients with conditions like brain edema or craniosynostosis. By calculating the relative waveform of ICP, this method seeks to enhance patient safety and comfort while delivering accurate measurements. The study focuses on patients who already have an ICP probe inserted for clinical reasons.
Who should consider this trial
Good fit: Ideal candidates include patients with an inserted ICP probe for clinical purposes who can remain still and focus on a target.
Not a fit: Patients with glaucoma, retinopathy, or head tremors may not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could significantly reduce the risks associated with invasive ICP monitoring methods.
How similar studies have performed: Other studies have explored non-invasive methods for ICP monitoring, but this specific approach using video ophthalmoscopy is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Must be able to sit still and fix their eyes on a target in the VO objective. * ICP participants must have an inserted ICP probe for clinical purposes. Exclusion Criteria: * Diagnosis of glaucoma, retinopathy or head tremor.
Where this trial is running
Minneapolis, Minnesota
- University of Minnesota — Minneapolis, Minnesota, United States (Recruiting)
Study contacts
- Principal investigator: Igor Nestrasil, MD, PhD — University of Minnesota
- Study coordinator: Igor Nestrasil, MD, PhD
- Email: nestr007@umn.edu
- Phone: 612-625-0496
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.