Non-invasive imaging of skin lesions using advanced microscopy
Official title: Non-invasive Skin Imaging Using Multiphoton Microscopy
Run by University of California, Irvine · NCT01771718 · Data updated 2026-11-12
This study is testing a new imaging technique to see if it can safely and accurately capture details of skin lesions without needing a biopsy.
Quick facts
| Study type | Observational |
|---|---|
| Sex | All |
| Enrollment | 250 (estimated) |
| Sponsor | University of California, Irvine Academic / other |
| Locations | 1 site (Irvine, California) |
| Status | Recruiting |
| Started | April 2012 |
| Main results expected | December 2028 |
| Study ends | December 2028 |
| Registry record updated | August 31, 2026 |
| Trial ID | NCT01771718 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates include males and females of all ages who can understand and follow study instructions.
✕Probably not a fit
Patients who are pregnant will not benefit from this study due to exclusion criteria.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This pilot study utilizes multiphoton microscopy to non-invasively image both pigmented and non-pigmented skin lesions in humans. The goal is to characterize the morphological and functional features of these lesions without the need for invasive biopsies. Images obtained through this advanced imaging technique will be compared to those from standard histopathology to assess accuracy and effectiveness. The study aims to enhance the understanding of skin lesions and improve diagnostic methods.
Why it matters
Potential benefit: If successful, this approach could lead to more accurate and less invasive diagnostic methods for skin lesions.
How similar studies have gone: While this approach is innovative, similar studies using advanced imaging techniques have shown promise in improving diagnostic accuracy.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Male or Female all age groups * Ability to understand and carry out subject instructions Exclusion Criteria: * Pregnant women
Where it's running
-
Beckman Laser Institute Medical Clinic
Irvine, California, United States Recruiting
Study contacts
- Principal investigator: Kristen Kelly, MD — Beckman Laser Institute, UCI
- Study coordinator: Hanna Kim
- Email: hhkim3@uci.edu
- Phone: 949-824-2251
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.