Non-invasive imaging of skin lesions using advanced microscopy

Non-invasive Skin Imaging Using Multiphoton Microscopy

Observational University of California, Irvine · NCT01771718

This study is testing a new imaging technique to see if it can safely and accurately capture details of skin lesions without needing a biopsy.

Quick facts

Study typeObservational
Enrollment250 (estimated)
SexAll
SponsorUniversity of California, Irvine Academic / other
Locations1 site (Irvine, California)
Trial IDNCT01771718 on ClinicalTrials.gov

What this trial studies

This pilot study utilizes multiphoton microscopy to non-invasively image both pigmented and non-pigmented skin lesions in humans. The goal is to characterize the morphological and functional features of these lesions without the need for invasive biopsies. Images obtained through this advanced imaging technique will be compared to those from standard histopathology to assess accuracy and effectiveness. The study aims to enhance the understanding of skin lesions and improve diagnostic methods.

Who should consider this trial

Good fit: Ideal candidates include males and females of all ages who can understand and follow study instructions.

Not a fit: Patients who are pregnant will not benefit from this study due to exclusion criteria.

Why it matters

Potential benefit: If successful, this approach could lead to more accurate and less invasive diagnostic methods for skin lesions.

How similar studies have performed: While this approach is innovative, similar studies using advanced imaging techniques have shown promise in improving diagnostic accuracy.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Male or Female all age groups
* Ability to understand and carry out subject instructions

Exclusion Criteria:

* Pregnant women

Where this trial is running

Irvine, California

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Skin Lesion
Last reviewed 2026-06-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.