Clinical trial Recruiting at 1 site Observational Ages 18 and up

Non-invasive diagnostics for eye infections

Official title: New Non-invasive Cellular and Molecular Diagnostics of Microbial Keratitis

Run by Sorlandet Hospital HF · NCT06364878 · Data updated 2026-11-12

This study is testing new ways to quickly and accurately diagnose different types of eye infections to help people avoid vision loss and get better treatment.

Quick facts

Study typeObservational
Ages18 Years and up
SexAll
Enrollment125 (estimated)
SponsorSorlandet Hospital HF
Government
Locations1 site (Arendal)
StatusRecruiting
StartedAugust 23, 2023
Main results expectedMarch 1, 2025
Study endsApril 8, 2028
Registry record updatedApril 15, 2024
Trial IDNCT06364878 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are adults over 18 years old with clinically suspected infectious keratitis who can travel to the hospital.

Probably not a fit

Patients with a history of infectious keratitis in the last 6 months or significant corneal thinning may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study focuses on improving the diagnosis of infectious keratitis, a condition that can lead to vision loss. It aims to differentiate between the various subtypes of keratitis—bacterial, viral, fungal, or parasitic—using advanced diagnostic techniques such as in vivo confocal microscopy and tear film sampling. By providing more accurate information, the study seeks to enhance treatment effectiveness and reduce the need for invasive procedures. The goal is to break the cycle of nonspecific diagnosis and suboptimal treatment that often leads to worsening vision.

Why it matters

Potential benefit: If successful, this study could lead to more accurate diagnoses and effective treatments for patients suffering from infectious keratitis.

How similar studies have gone: While this approach is innovative, similar studies have shown promise in improving diagnostic accuracy for ocular infections.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Clinically suspected infectious keratitis in patients over 18 years of age
* Patients with acceptable travel distance to the hospital
* Patients accepting to be part of the study

Exclusion Criteria:

* Previously diagnosed infectious keratitis during the last 6 months
* Over 50 percent thinning of the cornea
* Previous use of antibiotics (other than Chloramphenicol)

Where it's running

  • Sorlandet hospital
    Arendal, Norway
    Recruiting

Study contacts

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.