Non-invasive brain stimulation to enhance motor response
Neuromodulation of Transcranial Pulse Stimulation on Primary Motor Cortex in Adults: A Randomized, Cross-over, Single-blind, Sham-controlled, Pilot Trial
This study is testing whether a new type of brain stimulation can improve movement and behavior in healthy adults.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 40 (estimated) |
| Ages | 18 Years to 65 Years |
| Sex | All |
| Sponsor | The Hong Kong Polytechnic University Academic / other |
| Locations | 1 site (Hong Kong, Hung Hom, Kowloon) |
| Trial ID | NCT06312930 on ClinicalTrials.gov |
What this trial studies
This clinical trial investigates the effects of transcranial pulse stimulation (TPS), a non-invasive brain stimulation technique, on the primary motor cortex in healthy adults. The study employs a randomized, cross-over, single-blind, sham-controlled design to assess how TPS modulates motor response and behavior. By focusing on a well-defined population, the trial aims to provide insights into the efficacy and mechanisms of TPS, which has shown promise in treating neuropsychiatric disorders in previous studies.
Who should consider this trial
Good fit: Ideal candidates for this study are healthy adults aged 18 to 65 who are right-handed and have no physical, neurological, or psychiatric disorders.
Not a fit: Patients with a background in neuroscience or those with contraindications to TPS, such as metal implants or certain medical conditions, may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved understanding and application of TPS for enhancing motor function in various populations.
How similar studies have performed: While TPS has shown beneficial effects in other clinical settings, this specific approach is novel and has not been extensively tested in controlled studies with healthy adults.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age 18 to 65 * No physical, neurological or psychiatric disorder * Right-handedness Exclusion Criteria: * Background with neuroscience * TPS and TMS contraindications, including metal implants, pregnancy, coagulation disorders, thrombosis, brain tumor, cortisone therapy up to 6 weeks before first stimulation, pacemakers or cochlear implants.
Where this trial is running
Hong Kong, Hung Hom, Kowloon
- Georg Kranz, PhD — Hong Kong, Hung Hom, Kowloon, Hong Kong (Recruiting)
Study contacts
- Principal investigator: Georg S. Kranz, PhD — The Polytechnic University
- Study coordinator: Georg Kranz, PhD
- Email: georg.kranz@polyu.edu.hk
- Phone: 27664838
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.