Nine-grid Zoning Method to guide vertebroplasty for osteoporotic vertebral fractures

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This interventional study compares a novel Nine-grid Zoning Method-assisted vertebroplasty with the traditional pedicle puncture approach. It aims to standardize the puncture path, shorten operative time, and reduce fluoroscopy, radiation exposure, and cement leakage without adding risk. Eligible participants are adults with a single-segment acute lumbar OVCF undergoing their first PVP, with complete preoperative imaging. The study will assess intraoperative puncture endpoints, procedure duration, radiation exposure, cement leakage, and overall safety. Lead investigators are based at Beijing Friendship Hospital, Capital Medical University, in Beijing.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Diagnosed with single-segment acute osteoporotic lumbar vertebral compression fracture (L1-L5), confirmed by typical MRI manifestations: low signal on T1-weighted imaging and high signal on T2-weighted and STIR sequences.
* First-time reception of percutaneous vertebroplasty (PVP) surgery.
* Complete preoperative imaging data including X-ray, CT, and MRI/bone scan.
* Aged patients who voluntarily participate in the study and sign written informed consent.

Exclusion Criteria:

* Patients with old vertebral compression fractures or congenital pedicle dysplasia and lesions.
* With a history of bone tumors or other systematic bone metabolic diseases.
* CT examination shows incomplete or ruptured posterior wall of the fractured vertebral body.
* Failure to obtain signed informed consent.

Where it's running

• Beijing Friendship hospital, Capital Medical University
  Beijing, Beijing Municipality, China Recruiting

Study contacts

• Study coordinator: Qi Fei
• Email: spinefei@126.com
• Phone: +86 13641225060

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Vessel-X Bone Filling Container System for Vertebral Augmentation

  A new minimally invasive vertebral augmentation approach tests the Vessel-X device to see if it safely improves pain and function in people with osteoporotic vertebral compression fractures.

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• Vertebroplasty versus sham to see if activity and mobility improve after osteoporotic vertebral fractures

  This study tests whether vertebroplasty, compared with a sham procedure, increases physical activity and mobility in people aged 50+ with recent painful osteoporotic vertebral compression fractures.

  Recruiting Spine Centre of Southern Denmark · Kolding · NCT06776003

• Evaluating treatment outcomes for vertebral compression fractures

  This study is testing how well a procedure called vertebroplasty helps adults with osteoporosis-related spine fractures feel better and improve their quality of life.

  Recruiting Hirslanden Clinique Bois-Cerf Lausanne · Lausanne · NCT06670404

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.