New treatment for dizziness in people with multiple sclerosis

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study investigates the effects of a novel treatment aimed at alleviating dizziness in individuals with multiple sclerosis (MS). It compares daily personalized gaze stabilization training to intermittent gaze stability training to determine which is more effective. The intervention utilizes a technology called StableEyes, designed to enhance gaze stability through a gradual approach to vestibular exercises. By targeting the vestibulo-ocular reflex, the study aims to improve vision stability and reduce dizziness, ultimately enhancing the quality of life for participants.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Neurologist-confirmed diagnosis of primary progressive or relapsing and remitting MS per The 2017 Revision of the McDonald Criteria and the Magnetic Resonance Imaging in MS, or a healthy volunteer without a diagnosis of multiple sclerosis or any related neurological conditions
* Fluent in speaking and understanding English
* Subjects with multiple sclerosis have self-reported vestibular symptoms of dizziness, imbalance, and/or a history of at least two falls in the prior 12 months

Exclusion Criteria:

* Clinically isolated syndrome or radiologically isolated syndrome.
* Worsening MS symptoms during the prior 60 days
* Immunotherapy change in the prior 60 days
* Self-reported cognitive impairment that limits independence with basic and instrumental activities of daily living
* Systolic blood pressure \> 180 mmHg and/or diastolic blood pressure \> 90 mmHg at rest
* Static visual acuity with correction of worse than 1.0 logMAR
* Manifest ocular misalignment ≥ 5 diopters (e.g., tropia, lazy eye, strabismus}
* Convergence insufficiency
* Intra-nuclear ophthalmoplegia
* Vestibular Migraine
* Major orthopedic conditions that limit cervical spine range of motion or that alter walking
* Self-reported current or potential for pregnancy during enrollment
* Ongoing participation in vestibular rehabilitation for dizziness

Where it's running

• Emory Univeristy
  Atlanta, Georgia, United States Recruiting

Study contacts

• Principal investigator: Colin Grove, PT, MS, DPT, PhD — Emory University
• Study coordinator: Colin Grove, PT, DPT, MS, PhD
• Email: colin.r.grove@emory.edu
• Phone: (404) 712-8685

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.