New therapy for personality disorders

Evolutionary Systems Therapy for Early Onset of Personality Pathology: A Pilot Study on the Effectiveness and Feasibility With Adolescents and Young Adults

Not applicable Interventional Tages Onlus · NCT06415812

This study is testing a new therapy for people with personality disorders to see if it helps them improve their relationships and overall well-being over six months.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment21 (estimated)
Ages16 Years to 25 Years
SexAll
SponsorTages Onlus Academic / other
Locations1 site (Florence, FI)
Trial IDNCT06415812 on ClinicalTrials.gov

What this trial studies

This study investigates the feasibility and preliminary efficacy of Evolutionary Systems Therapy for individuals with various personality disorders. It includes three main actions: a case series involving adolescents, a case series for young adults, and an ecological momentary assessment to validate the therapy's conceptual model. Participants will undergo six months of psychotherapy, with assessments based on a dimensional model of personality. The goal is to gather data on interpersonal styles and the therapy's effectiveness across different age groups.

Who should consider this trial

Good fit: Ideal candidates are adolescents aged 16-19 and young adults aged 20-25 diagnosed with personality disorders.

Not a fit: Patients with schizophrenia spectrum disorders, bipolar disorders, autism spectrum disorder, intellectual disabilities, or those currently undergoing other treatments may not benefit from this study.

Why it matters

Potential benefit: If successful, this therapy could provide a novel treatment option for individuals suffering from personality disorders.

How similar studies have performed: Previous studies have shown promise for Evolutionary Systems Therapy in specific personality disorders, but this broader application is relatively novel.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Being diagnosed with personality pathology in accordance with Structured Clinical Interview for DSM-5 - Alternative Model of Personality Disorders Module I
* Being capable of read and sign the inform consent form

Exclusion Criteria:

* Being diagnosed with schizophrenia spectrum disorders and other psychosis
* Being diagnosed with bipolar disorders
* Being diagnosed with autism spectrum disorder
* Being diagnosed with intellectual disability
* Being under any psychopharmacological or psychosocial treatment

Where this trial is running

Florence, FI

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Personality Disorderscompassionmetacognitionpersonality disorderpersonality pathologyevolutionary psychopathology
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.