New pacing method to improve prediction of heart arrhythmias
"Right Ventricular Outflow Tract Posterior Septum Pacing" in Predicting Ventricular Outflow Tract Ventricular Tachycardia Origin: a Single-center, Prospective, Single Blind, Randomised Controlled Study
This study is testing a new pacing method to see if it can better predict where heart rhythm problems start in people with arrhythmias.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 100 (estimated) |
| Ages | 18 Years to 90 Years |
| Sex | All |
| Sponsor | Second Affiliated Hospital of Wenzhou Medical University Academic / other |
| Locations | 1 site (Wenzhou, Zhejiang) |
| Trial ID | NCT06360003 on ClinicalTrials.gov |
What this trial studies
This clinical trial aims to evaluate the effectiveness of a novel pacing technique, right ventricular outflow tract (RVOT) posterior septum pacing, in accurately predicting the origin of ventricular outflow tract (VOT) ventricular arrhythmias. The study will be conducted in two phases, enrolling a total of 200 patients. The first phase will compare the new pacing method's predictions against traditional electrocardiographic standards, while the second phase will assess the outcomes of patients undergoing radiofrequency catheter ablation using the new method versus conventional techniques.
Who should consider this trial
Good fit: Ideal candidates for this study are adults over 18 years old who have signed informed consent and are willing to participate in follow-up assessments.
Not a fit: Patients with severe cardiopulmonary, liver, or kidney dysfunction, or those unable to tolerate surgery, will not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could lead to more accurate identification of arrhythmia origins, improving treatment outcomes for patients with ventricular arrhythmias.
How similar studies have performed: While this approach is innovative, it builds on existing methods of arrhythmia management, and similar studies have shown promise in improving procedural outcomes.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Sign informed consent form * Age more than 18 years old * Able to understand the purpose of the experiment, voluntarily participate, willing to complete follow-up according to the requirement of the experimental protocol. Exclusion Criteria: * Severe cardiopulmonary, liver and kidney dysfunction, and inability to tolerate surgery due to coagulation dysfunction * Viral myocarditis, myocardial infarction or stroke with a course of less than six months * Simultaneously accompanied by malignant tumours, with an expected lifespan of less than or equal to 1 year * Severe thoracic deformity * Advanced age (more than 90 years old) * Other situations that the researcher deems unsuitable for participation in the study
Where this trial is running
Wenzhou, Zhejiang
- Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University — Wenzhou, Zhejiang, China (Recruiting)
Study contacts
- Principal investigator: Cheng Zheng, PhD — Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University
- Study coordinator: Cheng Zheng, PhD
- Email: zhengcheng_wzmufey@163.com
- Phone: 86-0577-85676609
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.