New method to close holes in the nasal septum
Official title: Nasal Septal Perforation Closure Using a 3-dimensional Fabricated Polycaprolactone Nasal Mesh
Run by Helwan University · NCT06439927 · Data updated 2026-11-12
This study is testing a new type of nasal mesh to see if it can help close holes in the nasal septum for people who need surgery.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years to 58 Years |
| Sex | All |
| Enrollment | 23 (estimated) |
| Sponsor | Helwan University Academic / other |
| Locations | 1 site (Cairo) |
| Status | Recruiting |
| Started | August 1, 2024 |
| Main results expected | September 2025 |
| Study ends | December 2025 |
| Registry record updated | November 5, 2024 |
| Trial ID | NCT06439927 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are patients scheduled for nasal septal perforation repair surgery.
✕Probably not a fit
Patients with known allergies to polycaprolactone or those who are pregnant or lactating may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This clinical trial investigates the effectiveness of a 3-dimensional fabricated nasal mesh in closing nasal septal perforations. The procedure involves placing the mesh between elevated mucoperichondrial flaps during repair surgery under general anesthesia. The position of the mesh will be confirmed using a nasal endoscope, and the status of the septal mucosa will be monitored monthly for three months following the surgery. This approach aims to improve surgical outcomes for patients with nasal septal perforations.
Why it matters
Potential benefit: If successful, this method could provide a more effective solution for patients suffering from nasal septal perforations.
How similar studies have gone: While there may be limited data on this specific approach, similar interventions using mesh materials have shown promise in other surgical applications.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients undergoing nasal septal perforation repair surgery. Exclusion Criteria: * Patients with known allergy to polycaprolactone. * Pregnancy or lactation.
Where it's running
-
Faculty of Medicine, Helwan University
Cairo, Egypt Recruiting
Study contacts
- Principal investigator: Mohamed H Sebaey, master degree — Helwan University
- Study coordinator: Mohamed H Sebaey, Master degree
- Email: mohamed.h757@hotmail.com
- Phone: 01008306356
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.